Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, 92093, USA.
Department of Medicine, University of California San Diego, La Jolla, 92093, USA.
Bioinformatics. 2021 May 5;37(5):731-733. doi: 10.1093/bioinformatics/btaa736.
A rich set of tools have recently been developed for performing genome-wide genotyping of tandem repeats (TRs). However, standardized tools for downstream analysis of these results are lacking. To facilitate TR analysis applications, we present TRTools, a Python library and suite of command line tools for filtering, merging and quality control of TR genotype files. TRTools utilizes an internal harmonization module, making it compatible with outputs from a wide range of TR genotypers.
TRTools is freely available at https://github.com/gymreklab/TRTools. Detailed documentation is available at https://trtools.readthedocs.io.
Supplementary data are available at Bioinformatics online.
最近开发了一套丰富的工具，用于进行串联重复（TR）的全基因组基因分型。然而，缺乏对这些结果进行下游分析的标准化工具。为了促进 TR 分析应用，我们提出了 TRTools，这是一个用于过滤、合并和 TR 基因型文件质量控制的 Python 库和命令行工具套件。TRTools 利用内部协调模块，使其与各种 TR 基因分型器的输出兼容。
TRTools 可在 https://github.com/gymreklab/TRTools 上免费获得。详细文档可在 https://trtools.readthedocs.io 上获得。
补充数据可在生物信息学在线获得。
