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在乌克兰注射毒品人群中实现 90-90-90 级联的阿片类激动剂治疗点获得综合服务的作用:国家级数据。

The role of access to integrated services at opioid agonist treatment sites in reaching 90-90-90 cascade in people who inject drugs in Ukraine: Country-level data.

机构信息

International Charitable Foundation 'Alliance for Public Health', 5 Dilova Str., Building 10A, Kyiv, 03150, Ukraine.

International Charitable Foundation 'Alliance for Public Health', 5 Dilova Str., Building 10A, Kyiv, 03150, Ukraine.

出版信息

Drug Alcohol Depend. 2020 Nov 1;216:108216. doi: 10.1016/j.drugalcdep.2020.108216. Epub 2020 Aug 8.

Abstract

INTRODUCTION

Opioid agonist treatment (OAT) is an effective means to prevent HIV transmission. Ukraine started integrating HIV services into OAT sites to improve people who inject drugs' (PWID) access to treatment.

METHODS

Data from the national registry of OAT patients (n = 9,983) were analyzed. These data are collected from all 179 OAT sites countrywide. For the cascade, HIV-positive OAT patients (n = 4,084) were stratified into two categories: OAT alone (received OAT at one site and antiretroviral therapy (ART) at different location, n = 1,789) and integrated care (received OAT and ART at one location, n = 2,295) for comparison.

RESULTS

Most HIV-positive OAT patients in Ukraine are male (85.6 %) and the mean age is 40.3 years old. The mean length of injecting before OAT is 17.2 years and the mean length on OAT is 4.2 years. All HIV-positive OAT clients are aware of their HIV status. The proportion of HIV-positive clients receiving ART was higher at integrated care sites compared to OAT alone sites (84.2 vs. 73.1 %, p- = 0.012); distribution of viral suppression among those receiving ART across the strata were 79.4 and 59.2 % for 'integrated care sites' vs. 'OAT only sites' respectively (p < 0.001).

CONCLUSIONS

This analysis clearly demonstrates much better progress towards the 90-90-90 goals among those OAT patients who receive integrated care services (both OAT and ART) at one site at each stage of the HIV care cascade as compared to receiving OAT and ART at different sites. There is an urgent need to further expand the integration of OAT and HIV services in Ukraine.

摘要

简介

阿片类激动剂治疗(OAT)是预防 HIV 传播的有效手段。乌克兰开始将艾滋病毒服务纳入 OAT 点,以改善注射吸毒者(PWID)获得治疗的机会。

方法

分析了全国 OAT 患者登记处的数据(n = 9983)。这些数据是从全国 179 个 OAT 点收集的。对于级联分析,HIV 阳性 OAT 患者(n = 4084)分为两类:单独 OAT(在一个地点接受 OAT 和不同地点的抗逆转录病毒治疗(ART),n = 1789)和综合护理(在一个地点接受 OAT 和 ART,n = 2295)进行比较。

结果

乌克兰大多数 HIV 阳性 OAT 患者为男性(85.6%),平均年龄为 40.3 岁。OAT 前注射的平均年限为 17.2 年,OAT 的平均年限为 4.2 年。所有 HIV 阳性 OAT 患者都知道自己的 HIV 状况。在综合护理点接受 ART 的 HIV 阳性患者比例高于单独 OAT 点(84.2%比 73.1%,p = 0.012);在接受 ART 的患者中,病毒抑制的分布在“综合护理点”和“仅 OAT 点”分别为 79.4%和 59.2%(p < 0.001)。

结论

与在不同地点接受 OAT 和 ART 的患者相比,在 HIV 护理级联的每个阶段在一个地点同时接受 OAT 和 ART 的 OAT 患者在实现 90-90-90 目标方面取得了明显更好的进展。乌克兰迫切需要进一步扩大 OAT 和艾滋病毒服务的整合。

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