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走过最近的硝化学术进展。

A Walk through Recent Nitro Chemistry Advances.

机构信息

Research Center for Molecular Design, Kochi University of Technology, Tosayamada, Kami, Kochi 782-8502, Japan.

出版信息

Molecules. 2020 Aug 12;25(16):3680. doi: 10.3390/molecules25163680.

DOI:10.3390/molecules25163680
PMID:32806751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7463458/
Abstract

Chemistry of nitro groups and nitro compounds has long been intensively studied. Despite their long history, new reactions and methodologies are still being found today. This is due to the diverse reactivity of the nitro group. The importance of nitro chemistry will continue to increase in the future in terms of elaborate synthesis. In this article, we will take a walk through the recent advances in nitro chemistry that have been made in past decades.

摘要

硝基和硝基化合物的化学性质一直受到广泛的研究。尽管它们的历史悠久,但今天仍在不断发现新的反应和方法。这是由于硝基的反应性多种多样。从精细合成的角度来看,未来硝基化学的重要性将继续增加。在本文中,我们将回顾过去几十年中硝基化学的最新进展。

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本文引用的文献

1
Asymmetric catalysis in direct nitromethane-free Henry reactions.直接无硝基甲烷亨利反应中的不对称催化
RSC Adv. 2020 Jan 13;10(4):2313-2326. doi: 10.1039/c9ra10263a. eCollection 2020 Jan 8.
2
Comparison of Substituting Ability of Nitronate versus Enolate for Direct Substitution of a Nitro Group.硝酮与烯醇盐对硝基直接取代的取代能力比较。
Molecules. 2020 Apr 28;25(9):2048. doi: 10.3390/molecules25092048.
3
Nitro-Perylenediimide: An Emerging Building Block for the Synthesis of Functional Organic Materials.硝基金刚烷二酰亚胺:一种新兴的功能有机材料合成构建块。
Molecules. 2020 Mar 19;25(6):1402. doi: 10.3390/molecules25061402.
4
Electrophilically Activated Nitroalkanes in Reactions With Carbon Based Nucleophiles.碳基亲核试剂反应中亲电活化的硝基烷烃
Front Chem. 2020 Feb 11;8:77. doi: 10.3389/fchem.2020.00077. eCollection 2020.
5
Recent Progress in Nitro-Promoted Direct Functionalization of Pyridones and Quinolones.硝基促进的吡啶酮和喹诺酮的直接功能化的最新进展。
Molecules. 2020 Feb 5;25(3):673. doi: 10.3390/molecules25030673.
6
Recent advances in transition metal-catalyzed C(sp)-H nitration.过渡金属催化的 C(sp^2)-H 硝化反应研究进展。
Org Biomol Chem. 2019 Feb 6;17(6):1351-1361. doi: 10.1039/c8ob02750a.
7
Reduction of Nitro Compounds Using 3d-Non-Noble Metal Catalysts.使用3d非贵金属催化剂还原硝基化合物
Chem Rev. 2019 Feb 27;119(4):2611-2680. doi: 10.1021/acs.chemrev.8b00547. Epub 2018 Dec 5.
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J Org Chem. 2018 Nov 16;83(22):13691-13699. doi: 10.1021/acs.joc.8b01865. Epub 2018 Nov 1.
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Nitro-Group-Containing Drugs.含硝基药物。
J Med Chem. 2019 Mar 28;62(6):2851-2893. doi: 10.1021/acs.jmedchem.8b00147. Epub 2018 Nov 1.
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α-Electrophilic Reactivity of Nitronates.硝酮的α-亲电性反应。
Chem Rec. 2018 Oct;18(10):1489-1500. doi: 10.1002/tcr.201800009. Epub 2018 Apr 18.