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G 组链球菌性心内膜炎:两例病例报告、文献综述及治疗建议

Group G streptococcal endocarditis: two case reports, a review of the literature and recommendations for treatment.

作者信息

Smyth E G, Pallett A P, Davidson R N

机构信息

Department of Medical Microbiology, St George's Hospital Medical School, London, U.K.

出版信息

J Infect. 1988 Mar;16(2):169-76. doi: 10.1016/s0163-4453(88)94022-4.

Abstract

Two cases of endocarditis caused by a group G streptococcus are reported and the literature on group G streptococcal endocarditis is reviewed. The onset of illness is usually acute and the portal of entry for the organism through the skin. The left side of the heart is mainly involved and in about 50% cases the endocarditis arises on a normal valve. Most patients develop complications, both embolic and cardiac, and the mortality is high (36%). We suggest that patients with proven group G streptococcal endocarditis should be treated with large doses of benzyl penicillin and with an aminoglycoside for not less than 4 weeks. Patients with complications should be referred to a cardiothoracic centre. We should be glad to know details of complications, treatment and outcome in other cases of group G streptococcal endocarditis.

摘要

报告了2例由G组链球菌引起的心内膜炎病例,并对G组链球菌心内膜炎的文献进行了综述。发病通常为急性,病菌通过皮肤进入体内。心脏左侧受累为主,约50%的病例心内膜炎发生在正常瓣膜上。大多数患者会出现栓塞和心脏方面的并发症,死亡率很高(36%)。我们建议,确诊为G组链球菌心内膜炎的患者应使用大剂量苄星青霉素和一种氨基糖苷类药物治疗不少于4周。有并发症的患者应转诊至心胸外科中心。我们很乐意了解其他G组链球菌心内膜炎病例的并发症、治疗及预后详情。

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