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一项前瞻性研究,比较改良包皮重建术与包皮环切术联合管状切开板尿道成形术治疗阴茎远端和中段尿道下裂的效果。

A prospective study comparing modified foreskin reconstruction versus circumcision with tubularized incised plate urethroplasty for distal and mid penile hypospadias.

作者信息

Pan Pradyumna

机构信息

Pediatric Surgery Unit, Ashish Hospital & Research Centre, Jabalpur, Madhya Pradesh, 482001, India.

出版信息

J Pediatr Urol. 2020 Oct;16(5):674.e1-674.e7. doi: 10.1016/j.jpurol.2020.07.040. Epub 2020 Aug 3.

Abstract

BACKGROUND

In Asian countries and the Hispanic populations, parents of many hypospadias patient demands prepuce to be saved. Foreskin reconstruction is a technique for achieving the nearly natural appearance of hypospadias penis. In most distal and selected mid-penile hypospadias it may be performed. Numerous specialists, however, support circumcision for the concern that foreskin reconstruction may endanger the repair of urethroplasty leading to the risk of formation of fistulas.

AIM

To evaluate the surgical complications and outcome of modified foreskin reconstruction (MFR) versus circumcision with tubularized incised plate urethroplasty for distal and mid penile hypospadias.

METHODS

This prospective comparative study included 80 children with distal and mid penile hypospadias treated from 2017 to 2019 in tertiary referral hospital. Group 1, n = 40 underwent TIPU and MFR, and Group 2 included 40 patients for TIPU with circumcision.

RESULTS

In group 1, patients ranged from 2.2 to 6.5 years (mean 4.6 ± 1.52 years) and in group 2 ranged 2.6-7 years (mean 4.59 ± 1.43 years). Specific to group 1 preputial edema was seen in 29 patients at 2nd weeks, completely disappeared by 8week. Retraction of prepuce was possible in 18 patients by 21 days and all but one by 6 months Foreskin wound gaping was seen in 1 at day 12 postoperatively and was repaired subsequently. Meatal stenosis was seen in one in both group, responded to urethral dilation by 6 weeks. Three patients from group 1 and 2 from group 2 developed urethral fistula which was subsequently closed. The complication rate was not statistically significant. Secondary phimosis was not seen in this study. A wide preputial opening was achieved during reconstruction in all patients in group 1.

DISCUSSION

One of the notable features, the absence of the prepuce, makes the patient conscious of the surgical procedure they had undergone. The specific complication of the preputial reconstruction is the presence of a non-retractile prepuce at the end of the surgery, secondary phimosis, preputial wound gaping, and dehiscence. In some patients, the distal portion of the prepuce becomes narrow, after vertical reconstruction. To prevent phimosis, the technique was improvised by taking transverse sutures in the distal part combined with midline approximation of the foreskin. This widens the preputial ring enabling smooth retraction of the reconstructed prepuce.

CONCLUSIONS

TIPU with MFR is an effective procedure for distal and selected mid penile hypospadias without increasing urethroplasty complications.

摘要

背景

在亚洲国家和西班牙裔人群中,许多尿道下裂患者的父母要求保留包皮。包皮重建是一种使尿道下裂阴茎外观接近自然的技术。在大多数远端和部分阴茎中段尿道下裂病例中可以实施该技术。然而,许多专家支持进行包皮环切术,因为担心包皮重建可能危及尿道成形术的修复,导致形成瘘管的风险。

目的

评估改良包皮重建术(MFR)与包皮环切术联合管状切开板尿道成形术治疗远端和阴茎中段尿道下裂的手术并发症及疗效。

方法

这项前瞻性对照研究纳入了2017年至2019年在三级转诊医院接受治疗的80例远端和阴茎中段尿道下裂患儿。第1组,n = 40例,接受TIPU和MFR,第2组包括40例行TIPU及包皮环切术的患者。

结果

第1组患者年龄在2.2至6.5岁之间(平均4.6 ± 1.52岁),第2组患者年龄在2.6至7岁之间(平均4.59 ± 1.43岁)。第1组特有的情况是,29例患者在术后第2周出现包皮水肿,至第8周完全消失。18例患者在21天时包皮可回缩,6个月时除1例患者外其余患者均能回缩。术后第12天有1例患者出现包皮伤口裂开,随后进行了修复。两组各有1例患者出现尿道口狭窄,6周时经尿道扩张后缓解。第1组有3例患者、第2组有2例患者发生尿道瘘,随后均愈合。并发症发生率无统计学意义。本研究中未观察到继发性包茎。第1组所有患者在重建过程中均实现了较宽的包皮开口。

讨论

一个显著特点是包皮缺失,这会使患者意识到自己接受过的手术。包皮重建的特定并发症包括术后末期包皮不能回缩、继发性包茎、包皮伤口裂开和裂开。在一些患者中,包皮垂直重建后远端部分变窄。为防止包茎,改进了技术,在远端采用横向缝合并结合包皮中线靠拢。这拓宽了包皮环,使重建后的包皮能够顺利回缩。

结论

TIPU联合MFR是治疗远端和部分阴茎中段尿道下裂的有效方法,且不会增加尿道成形术的并发症。

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