Department of Pediatric Oncology, Mayo Clinic Children's Center, Rochester, MN, USA.
Department of Neurological Surgery, University of Miami Miller School of Medicine, 1600 NW 10th Ave #1140, Miami, FL, 33136, USA.
Childs Nerv Syst. 2021 Feb;37(2):419-425. doi: 10.1007/s00381-020-04863-5. Epub 2020 Aug 17.
Atypical teratoid/rhabdoid tumor (ATRT) is a highly malignant embryonal tumor of the central nervous system (CNS) that occurs predominantly in children. More is being discovered about this disease to improve understanding and outcomes. The aim of this analysis was to evaluate citation and other bibliometric characteristics of the 50 most cited articles in the contemporary literature in order to better model the trajectory of our current efforts.
Elsevier's Scopus database was searched for the 50 most cited articles about ATRT. To look for trends, earliest 25 articles were separated from the latest 25 articles and then were compared. Various bibliometric parameters were summarized and compared using Pearson's chi-square and Mann-Whitney U tests.
The 50 most cited articles were published between 1990 and 2016, from 5 unique countries in 29 unique journals, with genetic and retrospective observational cohort studies the most common design (n = 11 each). Overall median values were as follows: citation count, 145.4 citations (range, 67-626); citation rate per year, 11.7 (range, 3.5-51.4); number of authors 12 (range, 1-95); with 32 (64%) originating from the USA. Compared with older articles, newer articles had statistically lower citation counts (101.8 vs 189.0; P < 0.01), higher number of authors (17.3 vs 6.6; P < 0.01), and were less likely published from the USA (40% vs 88%; P < 0.01) CONCLUSIONS: The 50 most cited articles about ATRT were characterized in this analysis. There was a distinct focus in these studies on the genetic composition and consequences of these tumors. Trends over time suggest greater impact will be had in highly collaborative efforts worldwide. Moving forward, it will be of great interest to see how the findings of these basic science finding will translate into future clinical studies.
非典型畸胎样/横纹肌样瘤（ATRT）是一种主要发生在儿童中的中枢神经系统（CNS）高度恶性胚胎肿瘤。为了提高对这种疾病的认识和治疗效果，人们对其进行了更多的研究。本分析的目的是评估当代文献中引用次数最多的 50 篇文章的引用和其他文献计量学特征，以便更好地模拟我们当前努力的轨迹。
在爱思唯尔的 Scopus 数据库中搜索关于 ATRT 的 50 篇引用次数最多的文章。为了寻找趋势，将最早的 25 篇文章与最新的 25 篇文章分开，然后进行比较。使用 Pearson's chi-square 和 Mann-Whitney U 检验总结和比较各种文献计量学参数。
这 50 篇引用次数最多的文章发表于 1990 年至 2016 年，来自 5 个不同国家的 29 种不同期刊，其中最常见的设计是遗传和回顾性观察队列研究（各 11 项）。总体中位数值如下：引用次数为 145.4 次（范围为 67-626）；每年引用率为 11.7 次（范围为 3.5-51.4）；作者人数为 12 人（范围为 1-95）；其中 32 篇（64%）来自美国。与较旧的文章相比，较新的文章的引用次数明显较低（101.8 与 189.0；P < 0.01），作者人数较多（17.3 与 6.6；P < 0.01），并且不太可能来自美国（40% 与 88%；P < 0.01）。
本分析对 ATRT 最受引用的 50 篇文章进行了特征描述。这些研究的一个明显重点是这些肿瘤的遗传组成和后果。随着时间的推移，全球范围内的高度协作努力将产生更大的影响。展望未来，很有趣的是看看这些基础科学发现的结果将如何转化为未来的临床研究。
