Department of Neurologic Surgery, Mayo Clinic, 200 1St St SW, Rochester, MN, 55905, USA.
Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, 55905, USA.
Childs Nerv Syst. 2024 Feb;40(2):453-462. doi: 10.1007/s00381-023-06157-y. Epub 2023 Sep 20.
Choroid plexus tumors (CPT) are relatively rare CNS tumors that primarily occur in children. They are classified as low-grade choroid plexus papilloma, including atypical ones, and high-grade choroid plexus carcinoma based on histological characteristics. There has been extensive academic research regarding these complex tumors. The goal of this work was to identify the 100 most-cited articles pertaining to CPTs in order to better understand the most impactful studies to date.
In August 2023, Elsevier's Scopus database was searched for the 100 most-cited articles about CPT. To look for trends, articles were classified as either basic science or clinical, and the earliest 50 articles were separated from the latest 50 articles and then were compared. Various bibliometric parameters were summarized and compared using Pearson's chi-square exact test and Wilcoxon rank sum test/Mann-Whitney U test.
The 100 most-cited articles were published between 1955 and 2016 in 53 different scientific journals, originating from 16 distinct countries. Over 75% of the articles were clinical in nature, and overall mean (range) values were as follows: citation count 78.5 (42-371), citation rate per year 3.4 (0.9-12), number of authors 6.2 (1-28). Newer articles had statistically higher citation rate (P < 0.01) and number of authors (P < 0.01) compared to their older counterparts. Additionally, while there was no significant difference in article focus (P = 0.64), there was a difference in study design (P < 0.01).
This study used citation number as a surrogate for article impact and identified the 100 most-cited CPT articles. New mutational analyses have allowed for further subgrouping and positive trends in collaboration shine hope for improvement in treatment outcomes and long-term survival.
脉络丛肿瘤（CPT）是相对罕见的中枢神经系统肿瘤，主要发生在儿童中。根据组织学特征，它们被分为低级别脉络丛乳头状瘤，包括非典型者，以及高级别脉络丛癌。针对这些复杂肿瘤，已经进行了广泛的学术研究。本研究的目的是确定 100 篇与 CPT 相关的被引频次最高的文章，以更好地了解迄今为止最具影响力的研究。
2023 年 8 月，在爱思唯尔的 Scopus 数据库中搜索了 100 篇关于 CPT 的被引频次最高的文章。为了寻找趋势，文章分为基础科学或临床，将最早的 50 篇文章与最新的 50 篇文章分开进行比较，然后比较各种文献计量参数，并使用 Pearson 卡方精确检验和 Wilcoxon 秩和检验/Mann-Whitney U 检验进行总结。
这 100 篇被引频次最高的文章发表于 1955 年至 2016 年，发表在 53 种不同的科学期刊上，来自 16 个不同的国家。超过 75%的文章为临床性质，总体平均值（范围）如下：引用次数 78.5（42-371），年引用率 3.4（0.9-12），作者人数 6.2（1-28）。与较旧的文章相比，较新的文章具有更高的引用率（P<0.01）和作者人数（P<0.01）。此外，尽管文章的重点没有显著差异（P=0.64），但研究设计存在差异（P<0.01）。
本研究使用引用次数作为文章影响的替代指标，确定了 100 篇被引频次最高的 CPT 文章。新的突变分析允许进一步细分，并为合作带来积极的趋势，这为改善治疗结果和长期生存带来了希望。
