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盆腔器官脱垂保留生育功能的 native-tissue 手术的最新进展。

Update in fertility-sparing native-tissue procedures for pelvic organ prolapse.

机构信息

San Paolo University Hospital, Milan, Italy.

EOC-Beata Vergine Hospital, Mendrisio, Switzerland.

出版信息

Int Urogynecol J. 2020 Nov;31(11):2225-2231. doi: 10.1007/s00192-020-04474-3. Epub 2020 Aug 18.

DOI:10.1007/s00192-020-04474-3
PMID:32809111
Abstract

Uterine-sparing prolapse surgery has been gaining back popularity with clinicians and patients. Although both prosthetic and native-tissue surgery procedures are described, the latter is progressively regaining a central role in pelvic reconstructive surgery, owing to a lack of mesh-related complications. Available native-tissue procedures have different advantages and pitfalls, as well as different evidence profiles. Most of them offer anatomical and subjective outcomes comparable with those of hysterectomy-based procedures. Moreover, native-tissue procedures in young women desiring childbearing allow to avoid synthetic material implantation, which may lead to potentially serious complications during pregnancy. As a consequence, we do think that offering a reconstructive native-tissue procedure for uterine preservation (with the exception of the Manchester procedure) is the safest option in women wishing for pregnancy. Sacrospinous ligament hysteropexy and high uterosacral ligament hysteropexy may be considered first-line options in consideration of the higher level of evidence and lack of adverse obstetrical outcomes.

摘要

保留子宫的脱垂手术在临床医生和患者中重新受到欢迎。虽然有假体和自体组织手术程序的描述,但由于缺乏与网片相关的并发症,后者在盆底重建手术中逐渐重新占据中心地位。现有的自体组织手术具有不同的优点和缺陷,以及不同的证据水平。它们中的大多数提供与基于子宫切除术的手术相当的解剖学和主观结果。此外,对于希望生育的年轻女性,自体组织手术可以避免植入合成材料,这可能会在怀孕期间导致潜在的严重并发症。因此,我们认为对于希望怀孕的女性,提供一种保留子宫的重建自体组织手术(除了曼彻斯特手术)是最安全的选择。骶骨固定悬吊带和高子宫骶骨固定悬吊带可以被认为是一线选择,因为它们具有更高的证据水平和缺乏不良产科结局。

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Update in fertility-sparing native-tissue procedures for pelvic organ prolapse.盆腔器官脱垂保留生育功能的 native-tissue 手术的最新进展。
Int Urogynecol J. 2020 Nov;31(11):2225-2231. doi: 10.1007/s00192-020-04474-3. Epub 2020 Aug 18.
2
Evaluation of two vaginal, uterus sparing operations for pelvic organ prolapse: modified Manchester operation (MM) and sacrospinous hysteropexy (SSH), a study protocol for a multicentre randomized non-inferiority trial (the SAM study).两种保留阴道和子宫的盆腔器官脱垂手术的评估:改良曼彻斯特手术(MM)和骶棘韧带子宫固定术(SSH),一项多中心随机非劣效性试验的研究方案(SAM研究)
BMC Womens Health. 2019 Apr 2;19(1):49. doi: 10.1186/s12905-019-0749-7.
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Hysteropexy: an Option for the Repair of Pelvic Organ Prolapse.子宫固定术:盆腔器官脱垂修复的一种选择。
Curr Urol Rep. 2018 Feb 23;19(2):15. doi: 10.1007/s11934-018-0765-4.
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Evidence-Based Review of Vaginal Native Tissue Hysteropexy for Uterovaginal Prolapse.基于证据的阴道固有组织子宫阴道脱垂固定术综述。
Obstet Gynecol Surv. 2019 Jul;74(7):429-435. doi: 10.1097/OGX.0000000000000686.
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Role of Hysteropexy in the Management of Pelvic Organ Prolapse.子宫托在盆腔器官脱垂管理中的作用
Curr Urol Rep. 2022 Sep;23(9):175-183. doi: 10.1007/s11934-022-01101-0. Epub 2022 Jul 5.
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Uterosacral Ligament Hysteropexy for Uterine Didelphys: A Case Report.子宫骶骨韧带子宫双角固定术治疗子宫双角:病例报告。
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Transvaginal uterosacral ligament hysteropexy versus hysterectomy plus uterosacral ligament suspension: a matched cohort study.经阴道子宫骶骨韧带固定术与子宫切除术加子宫骶骨韧带悬吊术比较:一项匹配队列研究。
Int Urogynecol J. 2020 Sep;31(9):1867-1872. doi: 10.1007/s00192-019-04206-2. Epub 2019 Dec 17.
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Sacrospinous hysteropexy versus vaginal hysterectomy with suspension of the uterosacral ligaments in women with uterine prolapse stage 2 or higher: multicentre randomised non-inferiority trial.骶棘韧带子宫固定术与子宫骶骨韧带悬吊的阴道子宫切除术治疗2期及以上子宫脱垂女性的多中心随机非劣效性试验
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Native tissue sacrospinous hysteropexy from an anterior approach.经阴道前路行固有组织骶棘韧带悬吊术。
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Laparoscopic Uterosacral Ligament Hysteropexy vs Total Vaginal Hysterectomy with Uterosacral Ligament Suspension for Anterior and Apical Prolapse: Surgical Outcome and Patient Satisfaction.腹腔镜子宫骶骨韧带固定术与经阴道全子宫切除术联合子宫骶骨韧带悬吊术治疗前位和前顶脱垂:手术结果和患者满意度。
J Minim Invasive Gynecol. 2020 Jan;27(1):88-93. doi: 10.1016/j.jmig.2019.02.012. Epub 2019 Feb 22.

引用本文的文献

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The presacral-uterosacral hysteropexy - a novel native tissue repair for pelvic organ prolapse.骶前-子宫骶骨悬吊术——一种用于盆腔器官脱垂的新型自体组织修复术。
Facts Views Vis Obgyn. 2025 Jun 27;17(2):130-137. doi: 10.52054/FVVO.2025.75.
2
National Survey on the Management of Genital Prolapse in Italy.意大利生殖器脱垂管理全国调查。
Int J Womens Health. 2024 Dec 17;16:2185-2193. doi: 10.2147/IJWH.S485350. eCollection 2024.
3
Impact on Sexual Function and Wish for Subsequent Pregnancy after Uterus-Preserving Prolapse Surgery in Premenopausal Women.
子宫脱垂保留子宫手术对绝经前女性性功能及后续妊娠意愿的影响
J Clin Med. 2024 Jul 13;13(14):4105. doi: 10.3390/jcm13144105.
4
Hysteropexy and Anterior Vaginal Native Tissue Repair in Women with Anterior and Central Compartment Prolapse: A Long Term Follow-Up.前盆腔和中盆腔脏器脱垂女性的子宫固定术及阴道前壁自体组织修复:长期随访
J Clin Med. 2023 Mar 28;12(7):2548. doi: 10.3390/jcm12072548.