Electrophysiology Unit, Cardiovascular Department, Poliambulanza Institute Hospital Foundation, Brescia, Italy.
Functional Cardiology Unit, Casa di Cura "Villa Azzurra", Siracusa, Italy.
J Interv Card Electrophysiol. 2021 Sep;61(3):559-566. doi: 10.1007/s10840-020-00835-6. Epub 2020 Aug 18.
To evaluate how the integration of intracardiac echocardiography (ICE) and ultrasound-guided femoral venipuncture (USGVC) may affect the safety of catheter ablation (CA) of atrial fibrillation (AF).
From a single center 374 patients with AF underwent 3D electroanatomic mapping-guided CA with or without the integration of ICE and USGVC. The primary endpoints were periprocedural complications, fluoroscopy time, and procedure time between the two groups.
The median age of patients was 60 years. Sixteen patients had major complications (4.3%); 10 of these (2.7%) had major vascular complications. Thirty-seven patients had minor complications (9.9%) that did not require intervention. There were fewer major complications in the CA with the aid of ICE and USGVC than in the conventional approach (1% vs 7%, p = 0.004). The combined approach required less fluoroscopy time than the conventional procedure (median with ICE + USGVC 14 min (interquartile range (IQR) 8-21) vs median without ICE + USGVC 22 min (IQR 17-32)), p < 0.001, and less radiofrequency time (median with ICE + USGVC 1686 s (IQR 1367-1998) vs median time without ICE + USGVC: 1792 s (IQR 1390-2400)), p = 0.012. After adjustment for confounding factors, only the use of ICE + USGVC (hazard ratio: 0.139; p = 0.05) was a significantly protective factor against major complications.
The use of ICE and USGVC in CA of AF is associated with significantly fewer major complications and lower fluoroscopy and radiofrequency time, so these aids increased the safety of the procedure.
评估心腔内超声(ICE)与超声引导股静脉穿刺(USGVC)联合应用对心房颤动(AF)导管消融(CA)安全性的影响。
从单中心选取 374 例 AF 患者,进行 3D 电生理标测指导下的 CA,其中部分患者联合 ICE 和 USGVC。主要终点为两组围手术期并发症、透视时间和手术时间。
患者的中位年龄为 60 岁。16 例患者出现严重并发症(4.3%),其中 10 例(2.7%)出现大血管并发症。37 例患者出现需要干预的小并发症(9.9%)。与常规方法相比,ICE 和 USGVC 辅助 CA 组的严重并发症更少(1% vs. 7%,p=0.004)。联合组的透视时间比常规组少(ICE+USGVC 中位数 14 分钟(IQR 8-21),无 ICE+USGVC 中位数 22 分钟(IQR 17-32),p<0.001),射频时间也更少(ICE+USGVC 中位数 1686 秒(IQR 1367-1998),无 ICE+USGVC 中位数 1792 秒(IQR 1390-2400),p=0.012)。调整混杂因素后,只有 ICE+USGVC 的使用(危险比:0.139;p=0.05)是严重并发症的显著保护因素。
在 AF 的 CA 中使用 ICE 和 USGVC 可显著减少严重并发症,降低透视和射频时间,从而提高手术安全性。