Urology Service, Hospital del Trabajador, Santiago, Chile.
Service of Urology, Hospital Dr. Sótero del Río, Santiago, Chile.
World J Urol. 2021 Jun;39(6):2099-2106. doi: 10.1007/s00345-020-03399-2. Epub 2020 Aug 18.
Injury to the external sphincter during urethroplasty at or near the membranous urethra can result in incontinence in men whose internal sphincter mechanism has been compromised by previous benign prostatic hyperplasia (BPH) surgery. We present outcomes of a novel reconstructive procedure, incorporating a recent anatomic discovery revealing a connective tissue sheath between the external sphincter and membranous urethra, which provides a surgical plane allowing for intrasphincteric bulbo-prostatic urethroplasty (ISBPA) with continence preservation.
Stricture at or near the membranous urethra after transurethral resection (TURP) or open simple prostatectomy (OSP) was reconstructed with ISBPA. The bulbomembranous junction is approached dorsally with a bulbar artery sparing approach and the external sphincter muscle is carefully reflected, exposing the wall of the membranous urethra. Gentle blunt dissection along this connective tissue plane allows separating the muscle away up to the prostatic apex, where healthy urethra is found for anastomosis.
From January 2010 to August 2019, 40 men (18 after TURP and 22 after OSP) underwent ISBPA at a single institution. Mean age was 67 years (54-82). Mean stricture length was 2.6 cm (1-6) with obliterative stricture identified in 10 (25%). At a mean follow-up of 53 months (10-122), 36 men (90%) are free of stricture recurrence and 34 (85%) were completely dry or using one security pad.
This novel intrasphincteric urethroplasty technique for stricture following BPH surgery is feasible and safe, allowing successful reconstruction with continence preservation in most patients. A larger series and reproduction in other centers is needed.
在膜部尿道或其附近进行尿道成形术时,如果损伤了外括约肌,而这些男性的内括约肌机制已经因先前的良性前列腺增生(BPH)手术而受损,则可能导致尿失禁。我们提出了一种新的重建手术方法的结果,该方法结合了最近的解剖学发现,即外括约肌和膜部尿道之间存在结缔组织鞘,这为括约肌内球部前列腺尿道成形术(ISBPA)提供了一个手术平面,同时保持了控尿功能。
经尿道前列腺切除术(TURP)或开放性单纯前列腺切除术(OSP)后在膜部尿道或其附近发生的狭窄采用 ISBPA 进行重建。采用球动脉保留方法从背侧接近球膜交界处,并小心地反射外括约肌,暴露膜部尿道壁。沿着这个结缔组织平面进行温和的钝性分离,允许将肌肉分离到前列腺顶点,在那里可以找到健康的尿道进行吻合。
从 2010 年 1 月到 2019 年 8 月,在一家单中心机构,40 名男性(18 名在 TURP 后,22 名在 OSP 后)接受了 ISBPA。平均年龄为 67 岁(54-82 岁)。平均狭窄长度为 2.6cm(1-6cm),其中 10 例(25%)为闭塞性狭窄。在平均随访 53 个月(10-122 个月)后,36 名男性(90%)无狭窄复发,34 名男性(85%)完全控尿或仅使用 1 个安全垫。
对于 BPH 手术后发生的狭窄,这种新的括约肌内尿道成形术技术是可行和安全的,大多数患者可以成功重建并保持控尿功能。需要更大的系列研究和在其他中心的复制。