下颌骨原发性弥漫性大 B 细胞淋巴瘤：一例报告。
Primary diffuse large B-cell lymphoma of the mandible: A case report.
机构信息
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kocaeli University, Kocaeli, Turkey.
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cyprus Health and Social Sciences University, Morphou, Cyprus.
出版信息
Gerodontology. 2020 Sep;37(3):307-311. doi: 10.1111/ger.12470.
INTRODUCTION
Lymphomas are a heterogeneous group of malignant neoplasms of lymphocytes and their precursor cells. Lymphoma is seen 3.5% of all intraoral malignancies and is the second most common neoplasm after the squamous cell carcinoma in the head and neck region. Diffuse large B-cell lymphomas (DLBCL), which is a subtype of non-Hodgkin lymphoma, are seen mostly in the paraoral region.
CASE PRESENTATION
An 82-year-old woman was referred with a localised swelling of the mandibular buccal mucosa for 3 months. Excisional biopsy revealed the diagnosis of DLBCL in the mandible and chemotherapy regimen started immediately. However, patient died during treatment.
CONCLUSIONS
Non-Hodgkin's lymphomas would be late- or misdiagnosed in the perioral region that may result poor prognosis.
简介
淋巴瘤是一组淋巴细胞及其前体细胞恶性肿瘤的异质性肿瘤。淋巴瘤占所有口腔内恶性肿瘤的 3.5%，是头颈部仅次于鳞状细胞癌的第二大常见肿瘤。弥漫性大 B 细胞淋巴瘤（DLBCL）是非霍奇金淋巴瘤的一种亚型，主要见于口腔周围区域。
病例介绍
一名 82 岁女性因下颌颊黏膜局部肿胀 3 个月就诊。切除活检显示下颌骨 DLBCL，立即开始化疗。然而，患者在治疗过程中死亡。
结论
口腔周围的非霍奇金淋巴瘤可能会被误诊或漏诊，导致预后不良。
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