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蠕虫病

Helminthiasis

作者信息

Al Amin A S M, Wadhwa Roopma

机构信息

Bangabandhu Sheikh Mujib Medical University

South Carolina Department of Mental Health

Abstract

The word "helminths" comes from the Greek meaning worm. The parasites that infect humans can be classified as heirlooms or souvenirs. Parasites that are inherited from ancestors in Africa are called Heirlooms, and those that are acquired from the animals during contact through our evolution, migrations, and agricultural practices are called souvenirs. In developing countries, the most common infectious agents of humans are these helminthic infections. More than a quarter of the world's population, that means approximately 2 billion people are affected by the helminthic parasite, and it is one of the major burdens of developing countries, especially in children. There are two major phyla of helminths known as nematodes and platyhelminths. Nematodes are also known as roundworms that include soil-transmitted helminths and the filarial worms that cause lymphatic filariasis (LF) and onchocerciasis. Other phyla platyhelminths also called flatworms, which include flukes schistosomes and tapeworms such as the pork tapeworm that causes cysticercosis. Flukes are known as trematodes, and tapeworms are known as cestodes. Soil-transmitted helminthiasis is a roundworm (), whipworm (), and hookworm ( and ). The soil-transmitted helminths (STHs), enter into the human body from contaminated soil that contains eggs of and . Some helminth can penetrate the skin directly (hookworm larvae). The diseases by helminths are neglected tropical diseases because they usually have insidious effects on growth and development. Also, the study of these diseases receives less than 1% of the global research budget.

摘要

“蠕虫”一词源于希腊语,意为“虫子”。感染人类的寄生虫可分为“传家宝”或“纪念品”两类。从非洲祖先那里遗传下来的寄生虫被称为“传家宝”,而在人类进化、迁徙及农业活动过程中通过与动物接触而获得的寄生虫则被称为“纪念品”。在发展中国家,人类最常见的感染源就是这些蠕虫感染。全球超过四分之一的人口,即约20亿人受到蠕虫寄生虫的影响,它是发展中国家的主要负担之一,对儿童影响尤甚。蠕虫主要有两个门类,即线虫和扁形虫。线虫也被称为蛔虫,包括土壤传播的蠕虫以及导致淋巴丝虫病(LF)和盘尾丝虫病的丝虫。另一门类扁形虫也被称为扁虫,包括吸虫(血吸虫)和绦虫,如导致囊尾蚴病的猪肉绦虫。吸虫也被称为吸虫纲,绦虫也被称为绦虫纲。土壤传播的蠕虫病是由蛔虫、鞭虫和钩虫引起的。土壤传播的蠕虫(STHs)从含有蛔虫和鞭虫卵的受污染土壤进入人体。有些蠕虫(钩虫幼虫)可直接穿透皮肤。蠕虫引发的疾病属于被忽视的热带病,因为它们通常对生长发育有潜在影响。此外,对这些疾病的研究获得的全球研究预算不到1%。

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Soil-transmitted helminthic vaccines: Where are we now?土壤传播的蠕虫疫苗:我们目前进展如何?
Acta Trop. 2023 Mar;239:106796. doi: 10.1016/j.actatropica.2022.106796. Epub 2022 Dec 29.

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