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铒激光换肤术

Laser Erbium-Yag Resurfacing

作者信息

Yumeen Sara, Hohman Marc H., Khan Tanzeela

机构信息

Warren Alpert Medical School of Brown University

Uniformed Services University/Madigan Army Medical Center

Abstract

With the passage of time, skin ages and accumulates photodamage. This results in loss of elasticity, changes in pigmentation, and the development of scarring from trauma, acne, and other insults. Laser skin resurfacing has become a gold standard option for the rejuvenation of facial skin’s texture, tone, and elasticity. For many years, carbon dioxide (CO2) lasers (wavelength 10,600 nm) were the only lasers available for laser skin rejuvenation; nowadays, there are many more options, including the solid-state erbium-doped yttrium aluminum garnet Er:YAG (2,940 nm), diode (810 and 940 nm), and erbium:glass lasers (1,540 and 1,550 nm). Er:YAG lasers were first FDA approved in 1996 for cutaneous resurfacing, and a comparative trial with CO2 lasers demonstrated that Er:YAG had equal efficacy with a trend towards more rapid recovery. Initially, short-pulse Er:YAG lasers were approved, with pulse lengths of 250-350 μs; however, variable and longer-pulse Er:YAG lasers with pulse widths of 500 μs to 10 ms were subsequently approved in 1999. The long-pulse and variable-pulse lasers introduced in 1999 were designed to provide enhanced coagulation, reducing bleeding compared to short-pulse Er:YAG treatments.

摘要

随着时间的推移,皮肤会老化并累积光损伤。这会导致弹性丧失、色素沉着改变,以及因创伤、痤疮和其他损伤而形成瘢痕。激光皮肤重建已成为改善面部皮肤质地、色泽和弹性的金标准选择。多年来,二氧化碳(CO2)激光(波长10,600纳米)是唯一可用于激光皮肤年轻化的激光;如今,有了更多选择,包括固态掺铒钇铝石榴石(Er:YAG)激光(2,940纳米)、二极管激光(810和940纳米)以及铒玻璃激光(1,540和1,550纳米)。Er:YAG激光于1996年首次获得美国食品药品监督管理局(FDA)批准用于皮肤重建,一项与CO2激光的对比试验表明,Er:YAG激光具有同等疗效,且恢复速度有更快的趋势。最初,批准的是短脉冲Er:YAG激光,脉冲长度为250 - 350微秒;然而,随后在1999年批准了脉冲宽度为从500微秒到10毫秒的可变长脉冲Er:YAG激光。1999年推出的长脉冲和可变脉冲激光旨在提供增强的凝血效果,与短脉冲Er:YAG治疗相比减少出血。

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