Chen Kee-Hsin, Tam Ka-Wai, Chen I-Fan, Huang Shihping Kevin, Tzeng Pei-Chuan, Wang Hsian-Jenn, Chen Chiehfeng Cliff
a Department of Nursing , Wan Fang Hospital, Taipei Medical University , Taipei , Taiwan.
b School of Nursing, College of Nursing , Taipei Medical University , Taipei , Taiwan.
J Cosmet Laser Ther. 2017 Aug;19(4):199-204. doi: 10.1080/14764172.2017.1288261. Epub 2017 Feb 6.
Laser resurfacing is used to minimize wrinkles, solar scars and sequelae of acne.
Purpose of the systematic review was to compare resurfacing outcomes of CO laser and erbium: yttrium aluminium garnet (erb:YAG) laser therapies.
Medline, Cochrane Library, EMBASE and Google Scholar databases were searched until 9 April 2015 using the following terms: laser, carbon dioxide/CO, facial wrinkles, rhytides and erbium-doped yttrium aluminium garnet/erbium:YAG/Er:YAG. Two-armed controlled split faced studies that compared CO laser and erbium:YAG laser in patients with mild-to-moderate facial wrinkles or rhytides were included.
The pooled data in this study and findings of other studies support the greater efficacy with the CO laser in improving facial wrinkles, but the erb:YAG laser was associated with a better complication profile compared with the CO laser. Except one case of hypopigmentation, other complications (i.e., erythema, hyperpigmentation and crusting) and their rates were reported by studies examining both lasers.
In general, the CO laser appeared to be more efficacious then the erb:YAG laser in treating facial wrinkles. Both lasers treatments were well tolerated.
激光表面重塑用于减少皱纹、日晒瘢痕和痤疮后遗症。
本系统评价的目的是比较二氧化碳（CO）激光和铒：钇铝石榴石（erb:YAG）激光治疗的表面重塑效果。
检索Medline、Cochrane图书馆、EMBASE和谷歌学术数据库至2015年4月9日，使用以下检索词：激光、二氧化碳/CO、面部皱纹、皱纹和掺铒钇铝石榴石/铒：钇铝石榴石/Er:YAG。纳入比较CO激光和铒：YAG激光治疗轻至中度面部皱纹或皱纹患者的双臂对照半脸研究。
本研究的汇总数据及其他研究结果支持CO激光在改善面部皱纹方面疗效更佳，但与CO激光相比，铒：YAG激光的并发症情况更好。除1例色素减退外，两项激光研究均报告了其他并发症（即红斑、色素沉着和结痂）及其发生率。
总体而言，CO激光在治疗面部皱纹方面似乎比铒：YAG激光更有效。两种激光治疗的耐受性均良好。
