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ZFP281 recruits polycomb repressive complex 2 to restrict extraembryonic endoderm potential in safeguarding embryonic stem cell pluripotency.

作者信息

Huang Xin, Bashkenova Nazym, Yang Jihong, Li Dan, Wang Jianlong

机构信息

Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, NY, 10032, USA.

Department of Cell, Developmental and Regenerative Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

出版信息

Protein Cell. 2021 Mar;12(3):213-219. doi: 10.1007/s13238-020-00775-x.

DOI:10.1007/s13238-020-00775-x
PMID:32812113
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7895869/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4591/7895869/7d71ee031403/13238_2020_775_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4591/7895869/cdc4c1d98d2f/13238_2020_775_Fig1a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4591/7895869/7d71ee031403/13238_2020_775_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4591/7895869/cdc4c1d98d2f/13238_2020_775_Fig1a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4591/7895869/7d71ee031403/13238_2020_775_Fig2_HTML.jpg

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本文引用的文献

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Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling.Zfp281 通过转录和表观遗传调控 Nodal 信号通路对小鼠上胚层成熟至关重要。
Elife. 2017 Nov 23;6:e33333. doi: 10.7554/eLife.33333.
2
PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation.PRC2 促进多能干细胞分化过程中启动子增强子功能所需的调控拓扑结构。
Cell Stem Cell. 2017 May 4;20(5):689-705.e9. doi: 10.1016/j.stem.2017.02.004. Epub 2017 Mar 9.
3
Zfp281 Coordinates Opposing Functions of Tet1 and Tet2 in Pluripotent States.
Cell Death Discov. 2023 Oct 25;9(1):396. doi: 10.1038/s41420-023-01691-9.
4
Zfp281 Inhibits the Pluripotent-to-Totipotent State Transition in Mouse Embryonic Stem Cells.Zfp281抑制小鼠胚胎干细胞中多能态向全能态的转变。
Front Cell Dev Biol. 2022 May 20;10:879428. doi: 10.3389/fcell.2022.879428. eCollection 2022.
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Reprogramming epiblast stem cells into pre-implantation blastocyst cell-like cells.重编程上胚层干细胞为植入前囊胚样细胞。
Stem Cell Reports. 2021 May 11;16(5):1197-1209. doi: 10.1016/j.stemcr.2021.03.016. Epub 2021 Apr 22.
Zfp281在多能状态下协调Tet1和Tet2的相反功能。
Cell Stem Cell. 2016 Sep 1;19(3):355-69. doi: 10.1016/j.stem.2016.05.025. Epub 2016 Jun 23.
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OSKM Induce Extraembryonic Endoderm Stem Cells in Parallel to Induced Pluripotent Stem Cells.OSKM 诱导胚胎外内胚层干细胞与诱导多能干细胞平行分化。
Stem Cell Reports. 2016 Apr 12;6(4):447-455. doi: 10.1016/j.stemcr.2016.02.003. Epub 2016 Mar 3.
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A XEN-like State Bridges Somatic Cells to Pluripotency during Chemical Reprogramming.XEN 样状态在化学重编程过程中连接体细胞核细胞到多能性。
Cell. 2015 Dec 17;163(7):1678-91. doi: 10.1016/j.cell.2015.11.017. Epub 2015 Dec 10.
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Nucleic Acids Res. 2015 May 26;43(10):4833-54. doi: 10.1093/nar/gkv370. Epub 2015 Apr 20.
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Conversion from mouse embryonic to extra-embryonic endoderm stem cells reveals distinct differentiation capacities of pluripotent stem cell states.从小鼠胚胎向胚外内胚层干细胞的转化揭示了多能干细胞状态的不同分化能力。
Development. 2012 Aug;139(16):2866-77. doi: 10.1242/dev.078519. Epub 2012 Jul 12.