Lozano Francisco S, Muñoz Angel, de Las Heras José A, González-Porras José R
Department of Angiology and Vascular Surgery, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.
Department of Otorhinolaryngology, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain.
Head Neck. 2020 Dec;42(12):3538-3550. doi: 10.1002/hed.26421. Epub 2020 Aug 19.
Carotid paragangliomas are rare tumors. They are usually unique, non-secreting, resectable, and benign. However, additional rare cases of complex tumors (bilateral, secretory, nonresectable, or malignant) complicate the management and final outcomes.
Records of paragangliomas from our hospital are reviewed. Criteria defining complex paragangliomas have been previously defined. These are compared with those of the simple group.
Fifty patients, two groups: simple (n = 39) and complex (n = 11). The patients in the complex group were significantly younger (47.7 vs 63.8 years). Postoperative nerve complications (45.4% vs 6.3%) and mortality during follow-up (27.3% vs 0%) were significantly more common in the complex group. Vascular complications (0% vs 3.1%) and early mortality (0%) were similarly in both groups.
Patients with complex carotid paragangliomas are heterogeneous. The former are younger, exhibit a high degree of diagnostic and therapeutic complexity, and have poorer morbidity and mortality. Surgical experience and interdisciplinary collaboration are essential.
颈动脉体瘤是罕见肿瘤。它们通常具有独特性、无分泌功能、可切除且为良性。然而，额外出现的复杂肿瘤（双侧、分泌性、不可切除或恶性）的罕见病例使治疗管理和最终结果变得复杂。
回顾我院颈动脉体瘤的记录。先前已定义了复杂颈动脉体瘤的标准。将这些标准与单纯组的标准进行比较。
50例患者，分为两组：单纯组（n = 39）和复杂组（n = 11）。复杂组患者明显更年轻（47.7岁对63.8岁）。复杂组术后神经并发症（45.4%对6.3%）和随访期间死亡率（27.3%对0%）明显更常见。两组血管并发症（0%对3.1%）和早期死亡率（0%）相似。
复杂颈动脉体瘤患者具有异质性。前者更年轻，诊断和治疗复杂性高，发病率和死亡率更高。手术经验和多学科协作至关重要。
