Archang Maani M, Lee Seung, Ziu Ismail, Clifton William, Miller David A, Jentoft Mark E, Janus Jeffrey R
Otolaryngology - Head and Neck Surgery, University of California, Los Angeles, Los Angeles, USA.
Neurological Surgery, Mayo Clinic, Jacksonville, USA.
Cureus. 2023 Jul 12;15(7):e41765. doi: 10.7759/cureus.41765. eCollection 2023 Jul.
Carotid body tumors (CBTs) are rare neoplasms of the neuroectoderm accounting for 0.6% of head and neck tumors, with a 2%-12.5% risk of malignancy. While surgical resection has been associated with a high rate of neurologic and vascular complications, it remains the mainstay of treatment for malignant CBTs. We present the case of a 40-year-old female with a 5-year history of progressively enlarging right-sided neck mass, with MRI and MRA showing a Shamblin grade III CBT encasement of the internal carotid artery (ICA). Blood flow was absent in the petrous segment of ICA, with great collateralization of brain blood supply, enabling en bloc resection of the tumor with a carotid bulb and ligation of the common carotid artery (CCA) without vascular reconstruction. Further, we describe the characteristics and current management for malignant CBTs, including surgical management, pre-surgical embolization, and adjuvant radiation therapy.
颈动脉体瘤（CBTs）是神经外胚层的罕见肿瘤，占头颈部肿瘤的0.6%，恶变风险为2% - 12.5%。虽然手术切除与较高的神经和血管并发症发生率相关，但它仍然是恶性CBTs的主要治疗方法。我们报告一例40岁女性病例，其右侧颈部肿块进行性增大5年，MRI和MRA显示为Shamblin III级CBT，包绕颈内动脉（ICA）。ICA岩骨段无血流，脑供血有大量侧支循环，从而能够在不进行血管重建的情况下将肿瘤与颈动脉球一并整块切除，并结扎颈总动脉（CCA）。此外，我们描述了恶性CBTs的特征和当前治疗方法，包括手术治疗、术前栓塞和辅助放疗。
