• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Inhaled nitric oxide in mechanically ventilated patients with COVID-19.

作者信息

Ferrari Michele, Santini Alessandro, Protti Alessandro, Andreis Davide T, Iapichino Giacomo, Castellani Gianluca, Rendiniello Valerio, Costantini Elena, Cecconi Maurizio

机构信息

Department of Anesthesia and Intensive Care, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy.

Department of Anesthesia and Intensive Care, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.

出版信息

J Crit Care. 2020 Dec;60:159-160. doi: 10.1016/j.jcrc.2020.08.007. Epub 2020 Aug 11.

DOI:10.1016/j.jcrc.2020.08.007
PMID:32814271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7417286/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4616/7417286/3b64919a6966/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4616/7417286/3b64919a6966/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4616/7417286/3b64919a6966/gr1_lrg.jpg

相似文献

1
Inhaled nitric oxide in mechanically ventilated patients with COVID-19.新型冠状病毒肺炎机械通气患者吸入一氧化氮治疗
J Crit Care. 2020 Dec;60:159-160. doi: 10.1016/j.jcrc.2020.08.007. Epub 2020 Aug 11.
2
Noninferiority of Inhaled Epoprostenol to Inhaled Nitric Oxide for the Treatment of ARDS.吸入依前列醇与吸入一氧化氮治疗急性呼吸窘迫综合征的非劣效性
Ann Pharmacother. 2015 Oct;49(10):1105-12. doi: 10.1177/1060028015595642. Epub 2015 Jul 17.
3
Phosphodiesterase-3 inhibition prevents the increase in pulmonary vascular resistance following inhaled nitric oxide withdrawal in lambs.磷酸二酯酶-3抑制可预防羔羊吸入一氧化氮撤离后肺血管阻力的增加。
Pediatr Crit Care Med. 2004 May;5(3):234-9. doi: 10.1097/01.pcc.0000124021.25393.2d.
4
Effect of nitric oxide in meconium aspiration syndrome after treatment with surfactant.一氧化氮在表面活性剂治疗后胎粪吸入综合征中的作用。
Crit Care Med. 1997 Oct;25(10):1744-7. doi: 10.1097/00003246-199710000-00027.
5
Inhaled nitric oxide decreases pulmonary soluble guanylate cyclase protein levels in 1-month-old lambs.吸入一氧化氮可降低1月龄羔羊肺组织中可溶性鸟苷酸环化酶蛋白水平。
J Thorac Cardiovasc Surg. 2004 May;127(5):1285-92. doi: 10.1016/j.jtcvs.2003.07.024.
6
Inhaled epoprostenol vs inhaled nitric oxide for refractory hypoxemia in critically ill patients.吸入前列环素与吸入一氧化氮治疗危重症患者难治性低氧血症。
J Crit Care. 2013 Oct;28(5):844-8. doi: 10.1016/j.jcrc.2013.03.006. Epub 2013 May 14.
7
Treatment of septic shock in rats with nitric oxide synthase inhibitors and inhaled nitric oxide.用一氧化氮合酶抑制剂和吸入一氧化氮治疗大鼠脓毒性休克。
Crit Care Med. 1998 Dec;26(12):2021-8. doi: 10.1097/00003246-199812000-00034.
8
Pulmonary uptake and modes of administration of inhaled nitric oxide in mechanically-ventilated patients.机械通气患者吸入一氧化氮的肺摄取及给药方式
Crit Care. 1998;2(1):9-17. doi: 10.1186/cc118.
9
The effect of inhaled nitric oxide on pulmonary ventilation-perfusion matching following smoke inhalation injury.吸入一氧化氮对烟雾吸入性损伤后肺通气-灌注匹配的影响。
J Trauma. 1994 Dec;37(6):893-8. doi: 10.1097/00005373-199412000-00004.
10
Nitric oxide supplied from a 10% source provides inhaled therapy without lowering inspired oxygen fraction.从10%的气源供应的一氧化氮可提供吸入疗法，而不会降低吸入氧分数。
Biomed Instrum Technol. 1997 Mar-Apr;31(2):164-8.

引用本文的文献

1
Inhaled nitric oxide for the treatment of COVID-19: an open-label, parallel, randomised controlled trial.吸入一氧化氮治疗新型冠状病毒肺炎：一项开放标签、平行分组、随机对照试验。
ERJ Open Res. 2025 Aug 26;11(4). doi: 10.1183/23120541.00006-2024. eCollection 2025 Jul.
2
Impact of low dose inhaled nitric oxide treatment in spontaneously breathing and intubated COVID-19 patients: a retrospective propensity-matched study.低剂量吸入一氧化氮治疗有自主呼吸和插管的 COVID-19 患者的影响：一项回顾性倾向评分匹配研究。
Crit Care. 2024 Oct 25;28(1):344. doi: 10.1186/s13054-024-05093-w.
3
Inhaled nitric oxide in moderate-to-severe COVID-19 acute respiratory distress syndrome: a retrospective cohort study.

本文引用的文献

1
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.新型冠状病毒肺炎的肺血管内皮细胞炎症、血栓形成和血管生成。
N Engl J Med. 2020 Jul 9;383(2):120-128. doi: 10.1056/NEJMoa2015432. Epub 2020 May 21.
2
Nitric oxide inhalation as an interventional rescue therapy for COVID-19-induced acute respiratory distress syndrome.吸入一氧化氮作为新型冠状病毒肺炎所致急性呼吸窘迫综合征的介入性抢救治疗手段。
Ann Intensive Care. 2020 May 20;10(1):61. doi: 10.1186/s13613-020-00681-9.
3
Hypoxaemia related to COVID-19: vascular and perfusion abnormalities on dual-energy CT.
吸入一氧化氮治疗中重度 COVID-19 急性呼吸窘迫综合征：一项回顾性队列研究。
Einstein (Sao Paulo). 2024 Aug 16;22:eAO0578. doi: 10.31744/einstein_journal/2024AO0578. eCollection 2024.
4
Unraveling the impact of nitric oxide, almitrine, and their combination in COVID-19 (at the edge of sepsis) patients: a systematic review.解析一氧化氮、阿米三嗪及其联合用药对新冠肺炎（处于脓毒症边缘）患者的影响：一项系统评价
Front Pharmacol. 2024 Jan 22;14:1172447. doi: 10.3389/fphar.2023.1172447. eCollection 2023.
5
The Potential Role of Nitric Oxide as a Therapeutic Agent against SARS-CoV-2 Infection.一氧化氮作为治疗 SARS-CoV-2 感染的潜在药物的作用。
Int J Mol Sci. 2023 Dec 5;24(24):17162. doi: 10.3390/ijms242417162.
6
Saying no to SARS-CoV-2: the potential of nitric oxide in the treatment of COVID-19 pneumonia.拒绝 SARS-CoV-2：一氧化氮在治疗 COVID-19 肺炎中的潜力。
Med Gas Res. 2024 Apr-Jun;14(2):39-47. doi: 10.4103/2045-9912.385414.
7
The effect of inhaled nitric oxide on shunt fraction in mechanically ventilated patients with COVID-19 pneumonia.吸入一氧化氮对新型冠状病毒肺炎机械通气患者分流分数的影响。
Afr J Thorac Crit Care Med. 2023 Aug 3;29(2). doi: 10.7196/AJTCCM.2023.v29i2.279. eCollection 2023.
8
Inhaled nitric oxide in patients with acute respiratory distress syndrome caused by COVID-19: treatment modalities, clinical response, and outcomes.新型冠状病毒肺炎所致急性呼吸窘迫综合征患者吸入一氧化氮治疗：治疗方式、临床反应及预后
Ann Intensive Care. 2023 Jun 27;13(1):57. doi: 10.1186/s13613-023-01150-9.
9
Inhaled Nitric Oxide in Acute Respiratory Distress Syndrome Subsets: Rationale and Clinical Applications.吸入一氧化氮治疗急性呼吸窘迫综合征亚组患者：原理与临床应用。
J Aerosol Med Pulm Drug Deliv. 2023 Jun;36(3):112-126. doi: 10.1089/jamp.2022.0058. Epub 2023 Apr 20.
10
Pregnancy and Severe ARDS with COVID-19: Epidemiology, Diagnosis, Outcomes and Treatment.COVID-19 相关妊娠与严重急性呼吸窘迫综合征：流行病学、诊断、结局与治疗。
Semin Fetal Neonatal Med. 2023 Feb;28(1):101426. doi: 10.1016/j.siny.2023.101426. Epub 2023 Mar 7.
与新型冠状病毒肺炎相关的低氧血症：双能CT上的血管和灌注异常
Lancet Infect Dis. 2020 Dec;20(12):1365-1366. doi: 10.1016/S1473-3099(20)30367-4. Epub 2020 Apr 30.
4
Clinical phenotypes of SARS-CoV-2: implications for clinicians and researchers.SARS-CoV-2 的临床表型：对临床医生和研究人员的启示。
Eur Respir J. 2020 May 21;55(5). doi: 10.1183/13993003.01028-2020. Print 2020 May.
5
Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations.2019 冠状病毒病（COVID-19）的重症监护管理：挑战与建议。
Lancet Respir Med. 2020 May;8(5):506-517. doi: 10.1016/S2213-2600(20)30161-2. Epub 2020 Apr 6.
6
COVID-19 Does Not Lead to a "Typical" Acute Respiratory Distress Syndrome.新冠病毒肺炎不会导致“典型的”急性呼吸窘迫综合征。
Am J Respir Crit Care Med. 2020 May 15;201(10):1299-1300. doi: 10.1164/rccm.202003-0817LE.
7
Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19).拯救脓毒症运动：2019 冠状病毒病（COVID-19）危重症成人管理指南。
Intensive Care Med. 2020 May;46(5):854-887. doi: 10.1007/s00134-020-06022-5. Epub 2020 Mar 28.
8
Treatment for severe acute respiratory distress syndrome from COVID-19.新型冠状病毒肺炎所致严重急性呼吸窘迫综合征的治疗
Lancet Respir Med. 2020 May;8(5):433-434. doi: 10.1016/S2213-2600(20)30127-2. Epub 2020 Mar 20.
9
The effect of inhaled nitric oxide in acute respiratory distress syndrome in children and adults: a Cochrane Systematic Review with trial sequential analysis.吸入一氧化氮治疗儿童和成人急性呼吸窘迫综合征的效果：一项 Cochrane 系统评价与试验序贯分析。
Anaesthesia. 2017 Jan;72(1):106-117. doi: 10.1111/anae.13628. Epub 2016 Oct 20.