Valerie T. J. Koh, Calvin J. Chiew, Khine Nandar, Anne Lee, Kelly Foo, Rachael Pung, Zubaidah Said, and Vernon Lee are with the Communicable Diseases Division, Ministry of Health, Singapore. Sean Wei Xiang Ong, Tau Hong Lee, David Chien Lye, and Yee-Sin Leo are with the National Centre for Infectious Diseases, Singapore. Lin Cui, Yi Kai Ng, and Raymond Lin are with the National Public Health Laboratory, National Centre for Infectious Diseases, Singapore.
Am J Public Health. 2020 Oct;110(10):1532-1534. doi: 10.2105/AJPH.2020.305820. Epub 2020 Aug 20.
A measles outbreak involving 19 adults in a home for the intellectually disabled occurred in Singapore in 2019. Further investigation, including a serological survey, was conducted. Mass vaccination and infection control measures were implemented, terminating further secondary transmission. Seropositivity among residents aged 40 to 49 years (90.7%; 95% confidence interval = 78.4%, 96.3%) was lower than among the Singapore adult population ( < .001). This sheltered population, like others previously reported in the literature, had lower measles immunity than the general community, possibly because of limited social interaction. Targeted catch-up vaccination for similarly vulnerable populations should be considered.
2019 年，新加坡一家智障人士收容所发生了一起涉及 19 名成年人的麻疹暴发事件。随后进行了进一步的调查，包括血清学调查。实施了大规模疫苗接种和感染控制措施，从而阻止了进一步的二次传播。40 至 49 岁居民的血清阳性率（90.7%；95%置信区间=78.4%，96.3%）低于新加坡成年人口（ < .001）。这个收容所人群与文献中之前报道的其他人群一样，麻疹免疫力低于一般社区，这可能是由于社交互动有限。应考虑针对类似弱势群体进行有针对性的补种疫苗。
