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本文引用的文献

1
Discussing Reproductive Plans with Healthcare Providers by Sexually Active Women Living with HIV in Western Ethiopia.与生活在埃塞俄比亚西部的性活跃 HIV 女性与医疗保健提供者讨论生殖计划。
AIDS Behav. 2020 Oct;24(10):2842-2855. doi: 10.1007/s10461-020-02833-1.
2
Subfertility among HIV-affected couples in a safer conception cohort in South Africa.南非安全性行为受孕队列中 HIV 感染者夫妇的生育力低下问题。
Am J Obstet Gynecol. 2019 Jul;221(1):48.e1-48.e18. doi: 10.1016/j.ajog.2019.02.040. Epub 2019 Feb 23.
3
A Systematic Review and Meta-analysis of Antiretroviral Therapy (ART) Adherence Interventions for Women Living with HIV.抗逆转录病毒疗法(ART)依从性干预措施对 HIV 感染者女性的系统评价和荟萃分析。
AIDS Behav. 2019 Aug;23(8):1998-2013. doi: 10.1007/s10461-018-2341-9.
4
Relative patterns of sexual activity and fertility among HIV positive and negative women-Evidence from 46 DHS.HIV 阳性和阴性妇女的性行为和生育模式的相对模式-来自 46 个 DHS 的证据。
PLoS One. 2018 Oct 17;13(10):e0204584. doi: 10.1371/journal.pone.0204584. eCollection 2018.
5
Implementation and outcomes of guideline revisions for the prevention of mother-to-child HIV transmission in Mother Support Programme, Addis Ababa, Ethiopia.在埃塞俄比亚亚的斯亚贝巴的母婴支持项目中,实施和评估预防母婴 HIV 传播指南修订的结果。
PLoS One. 2018 Jun 21;13(6):e0198438. doi: 10.1371/journal.pone.0198438. eCollection 2018.
6
Reduced fecundity in HIV-positive women.HIV 阳性妇女的生育力降低。
Hum Reprod. 2018 Jun 1;33(6):1158-1166. doi: 10.1093/humrep/dey065.
7
Healthcare provider attitudes regarding the provision of assisted reproductive services for HIV-affected couples in Addis Ababa, Ethiopia.埃塞俄比亚亚的斯亚贝巴医疗服务提供者对为受艾滋病影响的夫妇提供辅助生殖服务的态度。
Int J Gynaecol Obstet. 2018 Apr;141(1):45-51. doi: 10.1002/ijgo.12426. Epub 2018 Jan 28.
8
The relationship between HIV and fertility in the era of antiretroviral therapy in sub-Saharan Africa: evidence from 49 Demographic and Health Surveys.撒哈拉以南非洲抗逆转录病毒治疗时代的艾滋病毒与生育能力之间的关系:来自49项人口与健康调查的证据。
Trop Med Int Health. 2017 Dec;22(12):1542-1550. doi: 10.1111/tmi.12983. Epub 2017 Oct 24.
9
Fertility Intentions, Pregnancy, and Use of PrEP and ART for Safer Conception Among East African HIV Serodiscordant Couples.东非 HIV 血清不一致夫妇的生育意愿、怀孕情况以及使用暴露前预防和 ART 以实现更安全的受孕。
AIDS Behav. 2018 Jun;22(6):1758-1765. doi: 10.1007/s10461-017-1902-7.
10
Consensus statement: Supporting Safer Conception and Pregnancy For Men And Women Living with and Affected by HIV.共识声明:支持艾滋病毒感染者和受艾滋病毒影响的男性和女性实现更安全的生育和妊娠。
AIDS Behav. 2018 Jun;22(6):1713-1724. doi: 10.1007/s10461-017-1777-7.

埃塞俄比亚西部感染艾滋病毒妇女的生育情况:一项横断面研究。

Fertility among women living with HIV in western Ethiopia and : a cross-sectional study.

作者信息

Feyissa Tesfaye Regassa, Harris Melissa L, Forder Peta M, Loxton Deborah

机构信息

College of Health Science, Wollega University, Nekemte, Oromia, Ethiopia

Research Centre for Generational Health and Ageing, School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia.

出版信息

BMJ Open. 2020 Aug 20;10(8):e036391. doi: 10.1136/bmjopen-2019-036391.

DOI:10.1136/bmjopen-2019-036391
PMID:32819987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7443270/
Abstract

OBJECTIVE

This study aimed to examine fertility (live births) in the last 3 years and its associated factors among women living with HIV (WLHIV) in western Ethiopia .

DESIGN

Participants were recruited into a cross-sectional survey using systematic sampling.

SETTINGS

Four healthcare facilities in western Ethiopia were included.

PARTICIPANTS

Eligible participants were WLHIV of reproductive age (15-49 years) from western Ethiopia who found out about their HIV-positive status more than 3 years ago (N=866).

PRIMARY OUTCOME MEASURES

The fertility (live births) of HIV-positive women in the last 3 years was surveyed using face-to-face interviews (March-June 2018). Logistic regression analyses were conducted to examine factors influencing fertility in the last 3 years.

RESULTS

A total of 108 (12.5%) HIV-positive women gave birth to 121 live children in the last 3 years. Of these births, 18.2% were reported as mistimed at conception, while 26.4% were reported as unwanted. Of the live births, 8.3% ended in death. Of the 76 (62.8%) children with known HIV status born to HIV-positive women in the last 3 years, 7.9% were HIV-positive. In terms of predictors of fertility, women aged 15-24 years (adjusted OR (AOR) 2.72; 95% CI 1.14 to 6.49) and 25-34 years (AOR 4.34; 95% CI 2.61 to 7.21) had increased odds of fertility compared with women aged 35-49 years. Women using antiretroviral therapy (ART) for less than 5 years were more likely to have given birth in the last 3 years compared with those using ART for 10 years or more (AOR 2.96; 95% CI 1.19 to 7.36), even after controlling for age.

CONCLUSIONS

WLHIV in Ethiopia are having children and so it is imperative that safe conception strategies are readily available as well as support to reduce HIV-related risks for children born to these mothers. Strengthening reproductive health services for HIV-positive women in order to achieve their family planning goals is therefore important.

摘要

目的

本研究旨在调查埃塞俄比亚西部感染艾滋病毒的女性(WLHIV)过去3年的生育情况(活产)及其相关因素。

设计

采用系统抽样方法将参与者纳入横断面调查。

地点

纳入了埃塞俄比亚西部的四家医疗机构。

参与者

符合条件的参与者是来自埃塞俄比亚西部的育龄(15 - 49岁)感染艾滋病毒的女性,她们在3年多以前就已得知自己的艾滋病毒呈阳性状态(N = 866)。

主要观察指标

通过面对面访谈(2018年3月至6月)对艾滋病毒呈阳性的女性在过去3年的生育情况(活产)进行调查。进行逻辑回归分析以研究影响过去3年生育情况的因素。

结果

在过去3年中,共有108名(12.5%)艾滋病毒呈阳性的女性生育了121名活产婴儿。在这些出生案例中,18.2%的受孕时间被报告为不合时宜,而26.4%的婴儿是意外受孕。在活产婴儿中,8.3%夭折。在过去3年中,艾滋病毒呈阳性的女性所生的已知艾滋病毒感染状况的76名(62.8%)儿童中,7.9%呈艾滋病毒阳性。就生育的预测因素而言,与35 - 49岁的女性相比,15 - 24岁(调整后的比值比(AOR)2.72;95%置信区间1.14至6.49)和25 - 34岁(AOR 4.34;95%置信区间2.61至7.21)的女性生育几率增加。与使用抗逆转录病毒疗法(ART)达10年或更长时间的女性相比,使用ART少于5年的女性在过去3年中生育的可能性更大(AOR 2.96;95%置信区间1.19至7.36),即使在控制年龄因素之后也是如此。

结论

埃塞俄比亚的感染艾滋病毒的女性正在生育,因此必须随时提供安全的受孕策略,并提供支持以降低这些母亲所生孩子感染艾滋病毒的风险。因此,加强针对艾滋病毒呈阳性女性的生殖健康服务以实现她们的计划生育目标非常重要。