Consorci d'Aigües de Tarragona, N-340km 1.094, 43895 L'Ampolla, Spain; Department of Analytical Chemistry and Organic Chemistry, Universitat Rovira i Virgili, Marcel·lí Domingo s/n, Sescelades Campus, 43007 Tarragona, Spain.
Consorci d'Aigües de Tarragona, N-340km 1.094, 43895 L'Ampolla, Spain.
J Chromatogr A. 2020 Oct 11;1629:461485. doi: 10.1016/j.chroma.2020.461485. Epub 2020 Aug 13.
Per- and polyfluoroalkyl substances (PFASs) have been determined in waters intended for human consumption, causing concern due to their potential toxic effects in humans and the environment. Drinking water is acknowledged to be one of the major routes of exposure to PFASs, which has led to the implementation of regulatory guidelines for PFASs in drinking water. In this study a fast, simple, sensitive and cost-effective method is developed for the determination of 18 PFASs in river and drinking water. The proposed method consists of directly injecting 900 µL of sample into a liquid chromatograph coupled to a triple quadrupole mass analyser, which involves minimal sample treatment as the sample only needs to be filtered. The method was validated in influent and effluent water from a drinking water treatment plant. Strong matrix effects were found for some of the target PFASs, and matrix-matched calibration curves were performed to enable accurate (87-114%) and precise (%RSD between 3 and 18%) quantification (n = 5, at 5 and 75 ng·L) with very good sensitivity (method quantitation limits between 0.1 and 2.0 ng·L). The method was applied to water samples from the influent and effluent of a drinking water treatment plant located in Catalonia (Spain), as well as in tap water and bottled water. The most abundant PFAS in all the types of water was PFBA, which represents 48%, 49%, 66% and 69% of total PFASs found in influent, effluent, tap and bottled water respectively. Relative mean abundances and the sum of mean concentrations in influent and effluent water suggests poor removal of PFASs during drinking water treatment. The concentrations of PFASs in bottled waters were generally lower than those in tap waters.
全氟和多氟烷基物质 (PFASs) 已在供人类消费的水中被检出，由于其对人类和环境的潜在毒性影响而引起关注。饮用水被认为是接触 PFASs 的主要途径之一，这导致了饮用水中 PFASs 的监管指南的实施。在这项研究中，开发了一种快速、简单、灵敏和具有成本效益的方法，用于测定河流和饮用水中的 18 种 PFASs。该方法包括直接将 900µL 样品注入液相色谱仪，与三重四极杆质谱仪联用，由于仅需要对样品进行过滤，因此样品处理非常简单。该方法在饮用水处理厂的进水和出水进行了验证。发现一些目标 PFASs 存在很强的基质效应，因此进行了基质匹配校准曲线，以实现准确（87-114%）和精确（%RSD 在 3-18%之间）的定量（n=5，在 5 和 75ng·L 时），具有很好的灵敏度（方法定量限在 0.1-2.0ng·L 之间）。该方法应用于位于加泰罗尼亚（西班牙）的饮用水处理厂的进水和出水以及自来水和瓶装水的水样中。在所有水样中，最丰富的 PFAS 是 PFBA，分别占进水、出水、自来水和瓶装水中总 PFASs 的 48%、49%、66%和 69%。进水和出水中 PFASs 的相对平均丰度和总浓度之和表明，饮用水处理过程中 PFASs 的去除效果不佳。瓶装水中 PFASs 的浓度通常低于自来水中的浓度。
