血小板减少症与药物
Thrombocytopenia and drugs.
作者信息
Handagama P, Feldman B F
机构信息
Department of Pathology, University of California School of Medicine, San Francisco.
出版信息
Vet Clin North Am Small Anim Pract. 1988 Jan;18(1):51-65. doi: 10.1016/s0195-5616(88)50006-2.
PMID:3282385
Abstract
Thrombocytopenia is a relatively common side effect of drug therapy. The pathogenetic mechanisms of drug-induced thrombocytopenia are varied and sometimes poorly understood. Immunologic and other cytotoxic effects may result in decreased production and/or increased destruction of platelets. The pathogenesis of drug-induced thrombocytopenia is reviewed. Diagnosis and treatment are also discussed.
摘要
血小板减少症是药物治疗相对常见的副作用。药物性血小板减少症的发病机制多种多样，有时还不甚明了。免疫及其他细胞毒性作用可能导致血小板生成减少和/或破坏增加。本文对药物性血小板减少症的发病机制进行了综述。同时也讨论了其诊断和治疗方法。
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