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一种优化围手术期血糖管理的术中临床决策支持工具的影响

The Impact of an Intraoperative Clinical Decision Support Tool to Optimize Perioperative Glycemic Management.

作者信息

Li Gen, Dietz Chelsie J K, Freundlich Robert E, Shotwell Matthew S, Wanderer Jonathan P

机构信息

Department of Anesthesiology, Vanderbilt University Medical Center, 1211 21st Ave S, Nashville, TN, 37212, USA.

William Beaumont School of Medicine, Oakland University, Rochester, MI, USA.

出版信息

J Med Syst. 2020 Aug 21;44(10):175. doi: 10.1007/s10916-020-01643-1.

Abstract

With the transition from Vanderbilt's Perioperative Information Management System (VPIMS) to Epic's Best Practice Advisory (BPA) framework, a replacement intraoperative glucose clinical decision support (CDS) system was designed. We examined changes in the frequency of intraoperative glucose monitoring, hyper- and hypoglycemia rates in the post-anesthesia care unit (PACU), to determine the impact of the changes on glucose management. Data were collected into three phases: 1) VPIMS CDS, 2) No CDS, and 3) BPA CDS. One-way ANOVA was conducted to test the significance of changes in the frequency of glucose monitoring and abnormal glucose across phases. Interrupted time series segmented analysis was performed to assess the autocorrelation and trend over times. A total of 3706 cases were analyzed. The monitoring rate fell from 84.5% in VPIMS CDS to 67.6% in No CDS (p < .001) and increased to 83.1% in BPA CDS (p < .001). The PACU hyperglycemia rate increased from VPIMS CDS to No CDS (5.2% to 10.4%, p < .001) and decreased from No CDS to BPA CDS (10.4% to 7.2%, p = 0.031). The segmented analysis demonstrated immediate changes in the intraoperative monitoring frequency (p < .001) and postoperative hyperglycemia rate (p = 0.002) with the replacement of CDS. The temporary removal of CDS was associated with a significant reduction in intraoperative glucose monitoring and increased hyperglycemia in the PACU. Implementation of the BPA CDS led to a significant improvement in the intraoperative glucose monitoring and glucose management in the PACU.

摘要

随着从范德比尔特围手术期信息管理系统(VPIMS)向Epic最佳实践咨询(BPA)框架的转变,设计了一种替代的术中血糖临床决策支持(CDS)系统。我们检查了术中血糖监测频率的变化、麻醉后护理单元(PACU)中的高血糖和低血糖发生率,以确定这些变化对血糖管理的影响。数据收集分为三个阶段:1)VPIMS CDS,2)无CDS,3)BPA CDS。进行单因素方差分析以检验各阶段血糖监测频率和异常血糖变化的显著性。进行中断时间序列分段分析以评估随时间的自相关性和趋势。共分析了3706例病例。监测率从VPIMS CDS中的84.5%降至无CDS时的67.6%(p < 0.001),并在BPA CDS中升至83.1%(p < 0.001)。PACU高血糖率从VPIMS CDS到无CDS有所增加(从5.2%增至10.4%,p < 0.001),从无CDS到BPA CDS则有所下降(从10.4%降至7.2%,p = 0.031)。分段分析表明,随着CDS的更换,术中监测频率(p < 0.001)和术后高血糖率(p = 0.002)立即发生了变化。CDS的临时移除与术中血糖监测的显著减少以及PACU中高血糖的增加有关。BPA CDS的实施导致术中血糖监测和PACU中的血糖管理有显著改善。

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