Departments of Surgery and Oncology, Sections of General Surgery and Surgical Oncology, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada.
Departments of Surgery and Oncology, Sections of General Surgery and Surgical Oncology, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada.
Surgery. 2021 Mar;169(3):519-523. doi: 10.1016/j.surg.2020.07.008. Epub 2020 Aug 20.
Preoperative localization plays an important role in primary hyperparathyroidism. Sestamibi scans read by the radiologist as nonlocalizing were localizing when independently interpreted by the surgeon. The ability to perform dynamic surgeon-directed imaging, a of combination scans interpreted by the surgeon and surgeon-performed ultrasound done in tandem, appeared to improve preoperative localization. The objective was to evaluate scans read by the radiologist compared with dynamic surgeon-directed imaging.
A retrospective chart review was performed. Demographics, biochemistry, radiologist read scans, dynamic surgeon-directed imaging, operation, pathology, and follow-up results were collected. Localization rate, sensitivity, positive predictive value, and accuracy were calculated.
In the study, 474 charts met inclusion criteria. Only 63% of scans read by the radiologist were localizing, compared with 96% of dynamic surgeon-directed imaging. Overall dynamic surgeon-directed imaging was superior to scans read by the radiologist with 95% versus 60% sensitivity, 85% versus 85% positive predictive value, and 82% versus 54% accuracy. Dynamic surgeon-directed imaging remained superior when analyzing only those with single gland disease (n = 391). In addition, 85% of the 174 nonlocalized radiologist scans were correctly localized by dynamic surgeon-directed imaging.
The ability to perform an interpretation of both surgeon-performed ultrasound and scan interpreted by the surgeon in tandem improves the preoperative localization rate when compared with static reading of radiologist scans. This underscores the importance of having all primary hyperparathyroidism patients assessed by an experienced parathyroid surgical team, especially when the scans read by the radiologist is nonlocalizing.
术前定位在原发性甲状旁腺功能亢进症中起着重要作用。当外科医生独立解读时,放射科医生解读为非定位的锝-99m sestamibi 扫描为定位。外科医生进行的动态成像和与外科医生联合进行的扫描解读的组合、以及外科医生执行的超声检查的组合,似乎可以提高术前定位的准确性。目的是评估放射科医生解读的扫描与动态外科医生指导的成像。
进行了回顾性图表审查。收集了人口统计学、生物化学、放射科医生解读的扫描、动态外科医生指导的成像、手术、病理和随访结果。计算了定位率、灵敏度、阳性预测值和准确性。
在研究中,474 份图表符合纳入标准。只有 63%的放射科医生解读的扫描是定位的,而 96%的动态外科医生指导的成像为定位。总体而言,动态外科医生指导的成像优于放射科医生解读的扫描,其灵敏度为 95%对 60%,阳性预测值为 85%对 85%,准确性为 82%对 54%。当仅分析患有单腺疾病的患者(n=391)时,动态外科医生指导的成像仍然更具优势。此外,174 份放射科医生解读的非定位扫描中有 85%被动态外科医生指导的成像正确定位。
外科医生执行的超声和扫描解读的联合解读的能力,与放射科医生静态阅读扫描相比,提高了术前定位率。这强调了让所有原发性甲状旁腺功能亢进症患者接受经验丰富的甲状旁腺外科团队评估的重要性,尤其是当放射科医生解读的扫描为非定位时。