Röggla Veronika, Leydolt Christina, Schartmüller Daniel, Schwarzenbacher Luca, Meyer Elias, Abela-Formanek Claudette, Menapace Rupert
Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
Section for Medical Statistics, Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
Am J Ophthalmol. 2021 Jan;221:1-8. doi: 10.1016/j.ajo.2020.08.024. Epub 2020 Aug 21.
To assess the influence of artificial tears of different viscosity on K-readings prior to cataract surgery.
Prospective randomized crossover, before-and-after clinical study.
Setting: Department of Ophthalmology, Medical University of Vienna.
A total of 123 eyes of 80 patients prior to cataract surgery were assigned to 2 groups based on normal and dry eyes.
Two native baseline keratometries were followed by instillation of either high- or low-viscosity eye drops. Keratometry was repeated 30 seconds, 2 minutes, and 5 minutes after instillation.
Influence of eye drops of different viscosity in normal and dry eyes on short time K-readings.
Repeatability between native baseline measurements was high (standard deviation = 0.02 mm in normal and in dry eyes). In normal and dry eyes, a statistically significant increase in measurement variability after instillation of both low-viscosity and high-viscosity eye drops was observed (P < .01). Measurement variability was most pronounced between baseline measurement and 30 seconds and diminished over time. Variability of K-readings appeared higher in dry eyes compared with normal eyes. Astigmatism changed more than 0.5 diopters in 13.2% of normal eyes and 34.4% in dry eyes using eye drops of high viscosity.
Tear film-stabilizing eye drops prior to keratometry measurements influenced K-readings significantly, especially in dry eyes. A time period of more than 5 minutes should be allowed to pass after instillation of eye drops. The higher the viscosity of the eye drops, the stronger the influence and the longer its persistence.
评估不同黏度的人工泪液对白内障手术前角膜曲率读数的影响。
前瞻性随机交叉前后临床研究。
地点:维也纳医科大学眼科。
80例患者共123只眼在白内障手术前根据干眼和非干眼分为两组。
在进行两次原始基线角膜曲率测量后,滴入高黏度或低黏度滴眼液。滴入后30秒、2分钟和5分钟重复测量角膜曲率。
不同黏度滴眼液对正常眼和干眼短时间角膜曲率读数的影响。
原始基线测量之间的重复性很高(正常眼和干眼的标准差均为0.02mm)。在正常眼和干眼中,滴入低黏度和高黏度滴眼液后测量变异性均有统计学意义的增加(P<0.01)。测量变异性在基线测量和30秒之间最为明显,并随时间减小。与正常眼相比,干眼的角膜曲率读数变异性似乎更高。使用高黏度滴眼液时,13.2%的正常眼散光变化超过0.5屈光度,干眼为34.4%。
角膜曲率测量前使用的泪膜稳定滴眼液对角膜曲率读数有显著影响,尤其是在干眼中。滴入滴眼液后应等待超过5分钟。滴眼液的黏度越高,影响越强,持续时间越长。