Ryan P C, Gorey T F, Fitzpatrick J M
Department of Urology, Meath Hospital, Dublin, Ireland.
Eur Urol. 1988;14(2):141-4. doi: 10.1159/000472920.
Acute testicular torsion has been investigated using experimental models which either do not mimic torsion or cause parenchymal trauma. Valid conclusions regarding possible immunological activation cannot be made from such models. Techniques for experimental torsion in the rat are compared in this study to a standard venous occlusion model. Vascular dye injections and gross assessment were made at 0, 1 and 12 h. Testicular torsion of 720 degrees with fixation by a transmesorchial suture was the model which produced changes most similar to those in the venous occlusion model. This model causes torsion without parenchymal trauma and mimics acute testicular torsion more accurately than previously existing models.
急性睾丸扭转已通过实验模型进行研究，这些模型要么无法模拟扭转，要么会导致实质创伤。无法从这类模型得出关于可能的免疫激活的有效结论。本研究将大鼠实验性扭转技术与标准静脉闭塞模型进行了比较。在0小时、1小时和12小时进行血管染料注射和大体评估。采用经睾丸缝合固定的720度睾丸扭转是产生与静脉闭塞模型最相似变化的模型。该模型造成扭转而无实质创伤，比现有模型更准确地模拟急性睾丸扭转。
