Hattori Masami, Shirahane Kengo, Sakai Maya, Sassa Yukio, Nishihara Yunosuke, Aibe Hitoshi, Masuda Masanori, Mori Daisuke
Dept. of Breast Surgery, Saga-Ken Medical Centre Koseikan.
Gan To Kagaku Ryoho. 2020 Aug;47(8):1221-1224.
A 44-year-old woman experienced loss of vision and distorted vision in the right eye. After she visited our hospital, she was diagnosed with a right metastatic choroidal tumor. At the age of 35 years, she had undergone surgery for left breast cancer; as recurrence of the breast cancer was suspected, the patient was referred to our department. A CT scan revealed left axillary lymph node swelling, liver metastasis, and lung metastasis. Lymph node needle biopsy was performed under ultrasound guidance, and the pathological findings revealed recurrence of breast cancer. Combination chemotherapy of bevacizumab( BV)plus paclitaxel(PTX)was administered. After chemotherapy, the metastatic lesion had remarkably shrunk, as observed on a CT scan. Optical coherence tomography(OCT)revealed that the tumor was flattened in her right eye. Choroidal metastasis of breast cancer is rare. BV plus PTX therapy was effective for treating choroidal metastasis of breast cancer, and it should be followed by ophthalmological examination over time.
一名44岁女性右眼出现视力丧失和视物变形。她来我院就诊后，被诊断为右转移性脉络膜肿瘤。35岁时，她曾接受过左乳腺癌手术；由于怀疑乳腺癌复发，该患者被转诊至我科。CT扫描显示左腋窝淋巴结肿大、肝转移和肺转移。在超声引导下进行了淋巴结针吸活检，病理结果显示乳腺癌复发。给予贝伐单抗（BV）联合紫杉醇（PTX）的联合化疗。化疗后，CT扫描显示转移病灶明显缩小。光学相干断层扫描（OCT）显示她右眼的肿瘤变平。乳腺癌的脉络膜转移很少见。BV联合PTX疗法对治疗乳腺癌的脉络膜转移有效，且应定期进行眼科检查。
