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[关于严重烧伤后器官损伤综合防治的思考]

[Thoughts on comprehensive prevention and treatment of organ damage following severe burns].

作者信息

Huang Y S

机构信息

Department of Wound Repair, Institute of Wound Repair, Shenzhen People's Hospital, the First Affiliated Hospital of Southern University of Science and Technology, the Second Clinical Medical College of Jinan University, Shenzhen 518020, China.

出版信息

Zhonghua Shao Shang Za Zhi. 2020 Aug 20;36(8):647-650. doi: 10.3760/cma.j.cn501120-20200521-00278.

DOI:10.3760/cma.j.cn501120-20200521-00278
PMID:32829602
Abstract

Organ damage is currently the leading cause of death directly hindering the further improvement of cure rate of severe burn patients. This paper introduces some thoughts on the comprehensive prevention and treatment of organ damage after severe burns in the following aspects: the effective prevention and treatment of shock to reduce the organ damage to ischemia and anoxia, the treatment of inhalation injury to prevent and treat respiratory failure, the strengthened prevention and treatment of infection and immune conditioning to prevent the uncontrolled inflammatory response, the active treatment of burn wounds to prevent and treat wound sepsis, the strengthened support of organ function and nutrition to modulate the hypermetabolism, the strengthened research of basic and translational medicine for precise implementation. The author hopes this paper will be a meaningful reference for readers.

摘要

器官损害是目前直接阻碍重度烧伤患者治愈率进一步提高的首要死亡原因。本文从以下几个方面介绍一些关于重度烧伤后器官损害综合防治的思路:有效防治休克以减轻器官的缺血缺氧损害、治疗吸入性损伤以防治呼吸衰竭、强化感染防治及免疫调理以防止失控性炎症反应、积极处理烧伤创面以防治创面脓毒症、强化器官功能及营养支持以调控高代谢、加强基础与转化医学研究以精准施治。作者希望本文能为读者提供有意义的参考。

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引用本文的文献

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[Epidemiological characteristics and risk factors of sepsis development and death in patients with extremely severe burns].[特重度烧伤患者脓毒症发生及死亡的流行病学特征与危险因素]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2023 Jun 20;39(6):558-564. doi: 10.3760/cma.j.cn501225-20220806-00336.
2
Effects of enteral nutrition with different energy supplies on metabolic changes and organ damage in burned rats.不同能量供应的肠内营养对烧伤大鼠代谢变化和器官损伤的影响。
Burns Trauma. 2022 Nov 21;10:tkac042. doi: 10.1093/burnst/tkac042. eCollection 2022.
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Effects of Different Ratios of Carbohydrate-Fat in Enteral Nutrition on Metabolic Pattern and Organ Damage in Burned Rats.
不同碳水化合物-脂肪比例的肠内营养对烧伤大鼠代谢模式和器官损伤的影响。
Nutrients. 2022 Sep 4;14(17):3653. doi: 10.3390/nu14173653.
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Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Feb 20;38(2):147-155. doi: 10.3760/cma.j.cn501120-20210805-00269.
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[Establishment of an early risk prediction model for bloodstream infection and analysis of its predictive value in patients with extremely severe burns].[建立血流感染早期风险预测模型并分析其在特重度烧伤患者中的预测价值]
Zhonghua Shao Shang Za Zhi. 2021 Jun 20;37(6):530-537. doi: 10.3760/cma.j.cn501120-20210114-00021.