Department of Pharmacy, Baylor Scott & White Medical Center, The University of Texas at Austin, Temple, TX, USA.
Texas A&M Irma L. Rangel College of Pharmacy, Temple, TX, USA.
J Pharm Pract. 2022 Feb;35(1):70-74. doi: 10.1177/0897190020948685. Epub 2020 Aug 24.
Pharmacists have a positive effect on clinical outcomes in chronic disease state management, however, few studies have evaluated the effect that frequency of visits may have on diabetes biomarkers such as hemoglobin A1c and blood pressure readings.
Under the medication management program (MMP), patients with diabetes were seen monthly by pharmacists until early 2015, when time between visits was increased to every 3 months. A retrospective chart review was conducted to evaluate the primary outcome of the percent change in hemoglobin A1c and blood pressure after the change in visit frequency.
In the 303 patients enrolled, no statistical difference existed between the pre and post average A1c (p-value = 0.10). The intermediate average A1c was statistically lower from the preintervention mean A1c (p-value = 0.001) but not from the postintervention mean A1c (p-value = 0.30). No statistical differences were seen between systolic blood pressure and diastolic blood pressure.
Patients who have been seen by a clinical pharmacist more frequently (every month or every other month) for several years may be able to maintain their reduction in A1c with less-frequent visits (every 3 to 6 months).
药师在慢性病管理的临床结果中具有积极影响，但很少有研究评估就诊频率对糖化血红蛋白和血压读数等糖尿病生物标志物的影响。
在药物管理计划（MMP）下，糖尿病患者每月由药剂师就诊，直到 2015 年初，就诊时间增加到每 3 个月一次。进行了回顾性图表审查，以评估就诊频率改变后糖化血红蛋白和血压变化的主要结果。
在纳入的 303 名患者中，糖化血红蛋白的预平均值和后平均值之间没有统计学差异（p 值=0.10）。中间平均糖化血红蛋白明显低于干预前的平均糖化血红蛋白（p 值=0.001），但与干预后的平均糖化血红蛋白无差异（p 值=0.30）。收缩压和舒张压之间没有统计学差异。
已经由临床药师更频繁（每月或每两个月）就诊多年的患者可能能够通过减少就诊次数（每 3 至 6 个月一次）来维持糖化血红蛋白的降低。
