Levrini Virginia, Czosnyka Zofia, Lawes Indu, Kolias Angelos G, Mannion Richard
Neurosurgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, GBR.
Clinical Neurosciences, Addenbrooke's Hospital and University of Cambridge, Cambridge, GBR.
Cureus. 2020 Jul 19;12(7):e9287. doi: 10.7759/cureus.9287.
Assessing shunt function in vivo presents a diagnostic challenge. Infusion studies can be a cost-effective and minimally invasive aid in the assessment of shunt function in vivo. We describe a case of a patient who after a foramen magnum decompression for type I Chiari malformation developed bilateral posterior fossa subdural hygromas and mild hydrocephalus, eventually necessitating insertion of a ventriculoperitoneal shunt. The patient returned with symptoms that were concerning for infection of the shunt. A bedside infusion study helped confirm that the ventricular catheter was partially obstructed by in-growing choroid plexus, but also that the shunt was no longer necessary. Partial blockage due to in-growing choroid plexus was confirmed during surgery to remove the shunt. We discuss the behaviour of in-growing choroid plexus and how partial obstruction can be detected with the use of an infusion study, as well as how this compares to the pattern observed in complete shunt obstruction. The benefits of using infusion studies in the assessment of shunt function are also explored.
评估体内分流功能是一项诊断挑战。灌注研究在评估体内分流功能方面可能是一种经济高效且微创的辅助手段。我们描述了一例患者,该患者因I型Chiari畸形接受枕骨大孔减压术后出现双侧后颅窝硬膜下积液和轻度脑积水,最终需要插入脑室腹腔分流管。患者复诊时出现了提示分流管感染的症状。一项床旁灌注研究有助于证实脑室导管被内生性脉络丛部分阻塞,但同时也表明不再需要该分流管。在手术移除分流管时证实了内生性脉络丛导致的部分阻塞。我们讨论了内生性脉络丛的行为,以及如何通过灌注研究检测部分阻塞,以及这与完全分流阻塞时观察到的模式有何不同。还探讨了使用灌注研究评估分流功能的益处。