Department of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, China.
Suzhou Industrial Park Centers for Disease Control and Prevention, Suzhou, China.
J Med Food. 2020 Oct;23(10):1120-1127. doi: 10.1089/jmf.2020.4688. Epub 2020 Aug 20.
Dietary factors play a crucial role in the management of type 2 diabetes mellitus (T2DM) by reducing cardiovascular disease (CVD) risk. Therefore, we aimed to examine the associations between habitual green tea consumption and risk factors of CVD among T2DM patients. A total of 1013 patients with T2DM were included in a community-based cross-sectional study. Data on dietary habits, including tea consumption, were collected using a food frequency questionnaire. A multivariable logistic regression model was used to analyze the associations. In men, as compared with nongreen tea drinkers, odds ratios (ORs) (95% confidence interval [CI]) of nonalcoholic fatty liver disease (NAFLD) were 2.06 (95% CI, 1.20-3.55) for those with green tea consumption of once per day and 2.45 (95% CI, 1.31-4.58) for more than or equal to twice per day (-trend = .004); ORs (95% CI) of general obesity were 2.19 (95% CI, 1.02-4.68) and 2.70 (95% CI, 1.18-6.21), respectively (-trend = .021); whereas no such association was found in women. Sensitivity analysis according to self-awareness of their T2DM status revealed that the positive association between green tea consumption and general obesity was not reliable. Higher intake of green tea was still positively associated with NAFLD, but it only persisted in participants aged ≥52 years or the lower dietary quality subgroup in further analyses. Our findings suggest that tea consumption was associated with an increased risk of NAFLD among male T2DM patients aged 52 years or older, and those with lower dietary quality, which needs to be confirmed in future prospective studies.
饮食因素通过降低心血管疾病 (CVD) 风险在 2 型糖尿病 (T2DM) 的管理中起着至关重要的作用。因此，我们旨在研究习惯性饮用绿茶与 T2DM 患者 CVD 危险因素之间的关系。一项基于社区的横断面研究纳入了 1013 名 T2DM 患者。使用食物频率问卷收集了包括饮茶习惯在内的饮食习惯数据。使用多变量逻辑回归模型分析了相关性。在男性中，与非绿茶饮用者相比，每天饮用一次绿茶的非酒精性脂肪肝 (NAFLD) 的比值比 (OR) (95%置信区间 [CI]) 为 2.06 (95% CI, 1.20-3.55)，每天饮用两次或以上的 OR 为 2.45 (95% CI, 1.31-4.58) (-趋势 = .004)；OR (95% CI) 为普通肥胖症的分别为 2.19 (95% CI, 1.02-4.68) 和 2.70 (95% CI, 1.18-6.21)，呈趋势性差异 = .021)；而在女性中则没有这种相关性。根据对 T2DM 状态的自我认知进行敏感性分析表明，绿茶饮用与普通肥胖症之间的正相关关系并不可靠。进一步分析显示，较高的绿茶摄入量仍与 NAFLD 呈正相关，但仅在年龄≥52 岁或饮食质量较低的参与者中持续存在。我们的研究结果表明，在年龄≥52 岁或更高的男性 T2DM 患者以及饮食质量较低的患者中，饮茶与 NAFLD 风险增加有关，但需要在未来的前瞻性研究中进一步证实。
