Gautam Shankar, Gautam Arun, Chhetri Sahanshila, Bhattarai Urza
Ministry of Health and Population, Kathmandu, Nepal.
Ministry of Social Development, Gandaki Province, Nepal.
J Ayurveda Integr Med. 2022 Jan-Mar;13(1):100350. doi: 10.1016/j.jaim.2020.08.003. Epub 2020 Aug 17.
SARS-CoV-2 infection associated respiratory disease- COVID-19 has evolved into a pandemic but, being a new form of virus, pathogenesis of disease causation is not fully understood and drugs and vaccines against this virus are still being tested so that no effective drugs or vaccines have been advised by regulatory authority. In this context, the Ministry of AYUSH, Government of India has recommended '' to improve the immunity and combat the infection. Our objective of this literature review is to review the role of immunity in pathogenesis of COVID-19 and role of against the virus and regulation of immunity. Current review was conducted using a search of available literature on COVID-19 and immunity, , Ayurveda and COVID-19, , Coronavirus, SARS-CoV-2, immunomodulatory effects of medicinal plants; /Holy Basil/, /Cinnamon/, /Ginger/ and /Black Pepper/. Ayurveda, being an ancient science have both medicinal and cultural values and had stimulated our kitchen and influenced what we ate in different seasons and the remedies we used for common ailments. Herbs such as are the most commonly used and easily available drugs in home. Thus, due to its immune-modulatory, antiviral, anti-oxidant, anti-inflammatory, anti-platelet, anti-atherosclerotic, hepato-protective, reno-protective properties; seems to be effective in immuno-regulation for controlling viral infections like COVID-19. Further pre-clinical and clinical trials need to be done for the evaluation of safety and efficacy of this polyherbal formulation.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染相关的呼吸道疾病——新冠肺炎已演变成一场大流行，但作为一种新型病毒，其致病机制尚未完全明确，针对该病毒的药物和疫苗仍在试验中，因此监管机构尚未推荐有效的药物或疫苗。在此背景下，印度政府阿育吠陀部建议“增强免疫力以对抗感染”。我们进行本次文献综述的目的是回顾免疫力在新冠肺炎发病机制中的作用、对抗该病毒的作用以及免疫调节作用。本次综述通过检索关于新冠肺炎与免疫力、阿育吠陀与新冠肺炎、冠状病毒、SARS-CoV-2、药用植物的免疫调节作用；/圣罗勒/、/肉桂/、/生姜/和/黑胡椒/等方面的现有文献来进行。阿育吠陀作为一门古老的科学，兼具医学和文化价值，它激发了我们的厨房文化，影响了我们在不同季节的饮食以及我们用于治疗常见疾病的疗法。像[此处原文缺失植物名称]这样的草药是家中最常用且容易获取的药物。因此，[此处原文缺失植物名称]由于其免疫调节、抗病毒、抗氧化、抗炎、抗血小板、抗动脉粥样硬化、肝脏保护、肾脏保护特性；似乎在免疫调节以控制像新冠肺炎这样的病毒感染方面是有效的。需要进一步开展临床前和临床试验来评估这种多草药配方的安全性和有效性。
