Mitchell J E, Skelton M M
East Tennessee State University, Quillen-Dishner College of Medicine, Johnson City.
Am Fam Physician. 1988 May;37(5):195-207.
Infectious agents usually cause diarrhea by invading and damaging the intestinal mucosa or by producing enterotoxins that alter the secretory and absorptive capacities of the intestinal mucosa. Some infectious agents may do both. Physical malabsorption produced by proliferative outgrowth of bacteria or protozoa may also occur. Rotavirus is the most common cause of pediatric infectious diarrhea in the United States. Escherichia coli and Campylobacter species are the most common bacterial agents.
感染因子通常通过侵袭和损伤肠黏膜或产生改变肠黏膜分泌和吸收能力的肠毒素来引起腹泻。有些感染因子可能两种方式都采用。细菌或原生动物过度增殖导致的物理性吸收不良也可能发生。轮状病毒是美国儿童感染性腹泻最常见的病因。大肠杆菌和弯曲杆菌是最常见的细菌病原体。