Ghaswalla Parinaz K, D'Angelo John, Abu-Elyazeed Remon
GSK, Philadelphia, PA, USA.
Hum Vaccin Immunother. 2021 Mar 4;17(3):872-879. doi: 10.1080/21645515.2020.1794440. Epub 2020 Aug 26.
A systematic literature review of Medline and Embase databases was conducted to describe rotavirus (RV) vaccine coverage for a complete series, timing of receipt of all doses in the series, and predictors of RV vaccination coverage in the US for two licensed RV vaccines (RV1, RV5). Nine publications were included in the review. RV vaccination coverage rates of under 80% suggest RV vaccines are underutilized relative to the Healthy People 2020 target and other childhood vaccines. About 50-90% of children initiating RV vaccination complete the series and coverage for a complete series is lower for black and Hispanic children (vs. whites), uninsured or Medicaid insured (vs. privately insured), and for foreign-born (vs. US-born) children. Series completion is significantly greater in children receiving DTaP, RV1 (vs. RV5), and for those receiving routine care from a pediatrician. There is a need to design and implement better RV immunization strategies for US children.
对Medline和Embase数据库进行了系统的文献综述，以描述美国两种已获许可的轮状病毒（RV）疫苗（RV1、RV5）的全程系列轮状病毒疫苗接种覆盖率、系列中所有剂量的接种时间以及轮状病毒疫苗接种覆盖率的预测因素。该综述纳入了九篇出版物。低于80%的轮状病毒疫苗接种覆盖率表明，相对于《健康人民2020》目标和其他儿童疫苗，轮状病毒疫苗未得到充分利用。开始接种轮状病毒疫苗的儿童中，约50-90%完成了全程接种，黑人、西班牙裔儿童（与白人相比）、未参保或参加医疗补助保险的儿童（与参加私人保险的儿童相比）以及外国出生的儿童（与美国出生的儿童相比）的全程接种覆盖率较低。接种百白破疫苗、RV1（与RV5相比）的儿童以及接受儿科医生常规护理的儿童的系列完成率显著更高。有必要为美国儿童设计并实施更好的轮状病毒免疫策略。
