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组胺敏感性:一种未被普遍认识的引起喉咽反流症状和体征的原因——病例报告

Histamine Sensitivity: An Uncommon Recognized Cause of Living Laryngopharyngeal Reflux Symptoms and Signs-A Case Report.

作者信息

Alnouri Ghiath, Cha Nicholas, Sataloff Robert T

机构信息

Department of Otolaryngology-Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, PA, USA.

Drexel University College of Medicine, Philadelphia, PA, USA.

出版信息

Ear Nose Throat J. 2022 May;101(4):NP155-NP157. doi: 10.1177/0145561320951071. Epub 2020 Aug 26.

DOI:10.1177/0145561320951071
PMID:32845804
Abstract

A 45-year-old female who had undergone Nissen fundoplication for long-standing laryngopharyngeal reflux (LPR) developed episodes of coughing and throat clearing. Strobovideolaryngoscopy demonstrated evidence of LPR with a reflux finding score of 11. A cough workup including a chest X-ray and pulmonology consultation was negative. Consultation with a nutritionist revealed Histamine intolerance. Histamine-free diet resulted in marked improvement in patient's symptoms and examination.

摘要

一名45岁女性因长期喉咽反流(LPR)接受了nissen胃底折叠术,术后出现咳嗽和清嗓症状。频闪喉镜检查显示有LPR证据,反流发现评分为11分。包括胸部X光和肺科会诊在内的咳嗽检查均为阴性。咨询营养师后发现患者对组胺不耐受。无组胺饮食使患者症状和检查结果有显著改善。

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引用本文的文献

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Life (Basel). 2023 Jan 14;13(1):240. doi: 10.3390/life13010240.
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Histamine Intolerance-The More We Know the Less We Know. A Review.组胺不耐受——了解越多,困惑越多。一篇综述。
Nutrients. 2021 Jun 29;13(7):2228. doi: 10.3390/nu13072228.
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Histamine Intolerance Originates in the Gut.组胺不耐受源于肠道。
Nutrients. 2021 Apr 12;13(4):1262. doi: 10.3390/nu13041262.
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Reflux clinic: proof-of-concept of a Multidisciplinary European Clinic.反流诊所:欧洲多学科诊所的概念验证
Eur Arch Otorhinolaryngol. 2021 May;278(5):1713-1716. doi: 10.1007/s00405-021-06705-9. Epub 2021 Feb 23.