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温暖气候地区青年男性急性心肌梗死:临床特征和季节分布。

Acute Myocardial Infarction among Young Adult Men in a Region with Warm Climate: Clinical Characteristics and Seasonal Distribution.

机构信息

Department of Physical Therapy, Tzu Chi University, Hualien 97004, Taiwan.

Institute of Medical Sciences, Tzu Chi University, Hualien 97004, Taiwan.

出版信息

Int J Environ Res Public Health. 2020 Aug 24;17(17):6140. doi: 10.3390/ijerph17176140.

DOI:10.3390/ijerph17176140
PMID:32847005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7503405/
Abstract

The aim of this cross sectional study was to investigate the influence of the seasons on acute myocardial infarction (AMI) among young adult among young adults aged <45 years compared to old adults aged ≥45 years. The seasonal distribution of AMI hospital admissions among young adult men in eastern Taiwan was assessed. Data were extracted from 1413 male AMI patients from January 1994 to December 2015, including onset date, the average temperature (Tave) on the date of AMI hospitalization (AMI-Tave), and conventional risk factors, notably smoking, diabetes, hypertension, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, and body mass index (BMI). The 1413 cases were divided into two groups: the young group ( = 138, <45 y/o) and the older group ( = 1275, ≥45 y/o). The differences between groups were examined. Logistic regression analyses were used to evaluate the associations between the seasons and the AMI hospitalization among the young group. The young group showed significantly higher percentage of smokers, BMI, total cholesterol levels, and triglycerides levels but lower percentage of diabetes and hypertension than the older group ( < 0.05). AMI hospitalization in winter was significantly greater compared to the other seasons among the young group ( < 0.05). Winter hospitalization was significantly associated with the young group relative to the older group (adjusted OR 1.750; 95% CI 1.151 to 2.259), while winter AMI-Tave in the young group was similar to that in the older group. Young adult men diagnosed with AMI are more likely than older adult men to be smokers, obese, and show an onset dependent on winter but not low-temperature in a region with a warm climate.

摘要

本横断面研究旨在探讨与老年患者(≥45 岁)相比,年轻成年患者(<45 岁)的季节变化对急性心肌梗死(AMI)的影响。评估了台湾东部年轻成年男性 AMI 住院患者的季节性分布。1994 年 1 月至 2015 年 12 月,从 1413 例 AMI 男性患者中提取数据,包括发病日期、AMI 住院日期的平均气温(AMI-Tave)和常规危险因素,如吸烟、糖尿病、高血压、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、甘油三酯和体重指数(BMI)。1413 例患者分为两组:年轻组(=138,<45 岁)和老年组(=1275,≥45 岁)。比较了两组之间的差异。采用 logistic 回归分析评估了季节与年轻组 AMI 住院之间的关系。年轻组的吸烟者、BMI、总胆固醇和甘油三酯水平明显高于老年组,而糖尿病和高血压的比例明显低于老年组(<0.05)。与其他季节相比,年轻组冬季的 AMI 住院率明显更高(<0.05)。与老年组相比,冬季住院与年轻组显著相关(调整后的 OR 1.750;95% CI 1.151-2.259),而年轻组冬季 AMI-Tave 与老年组相似。与老年男性患者相比,年轻男性患者更易吸烟、肥胖,且发病与冬季而非低温有关,而在气候温暖的地区,这一现象可能与季节有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d73f/7503405/c756e8585ddb/ijerph-17-06140-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d73f/7503405/c756e8585ddb/ijerph-17-06140-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d73f/7503405/c756e8585ddb/ijerph-17-06140-g001.jpg

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