Framingham Heart Study, 73 Mount Wayte Avenue, Framingham, Massachusetts 01702-5827, USA.
Department of Cardiology, Herlev and Gentofte Hospital, Niels Andersens Road 65, 2900 Hellerup, Denmark.
Nat Rev Cardiol. 2018 Apr;15(4):230-240. doi: 10.1038/nrcardio.2017.154. Epub 2017 Oct 12.
In the past 2 decades, a high prevalence of risk factors for cardiovascular disease, such as obesity, physical inactivity, and poor diet, has been observed among young individuals living in developed countries. The rate of substance abuse (opioids, cocaine, electronic cigarettes, and anabolic steroids) is also increasing among young adults, whereas cigarette smoking might be declining. Among younger individuals (aged 18-50 years), the incidence of cardiovascular diseases over the same time period has either been steady or has increased, in contrast to the trend towards a lower incidence of cardiovascular disease in adults aged >50 years. Current observations might, therefore, be used to forecast a potential epidemic of cardiovascular disease in the near future as the younger segment of the population ages. In this Review, we discuss the burden of risk factors for ischaemic heart disease, heart failure, atrial fibrillation, and sudden cardiac death among young adults aged 18-45 years. Furthermore, we discuss the prevalence, incidence, and temporal trends of various cardiovascular diseases among this young segment of the population.
在过去的 20 年中,在发达国家生活的年轻人中,肥胖、身体活动不足和不良饮食等心血管疾病的危险因素的流行率很高。年轻人中滥用药物(阿片类药物、可卡因、电子烟和合成代谢类固醇)的比例也在增加,而吸烟的比例可能正在下降。在年轻人群体(18-50 岁)中,同期心血管疾病的发病率保持稳定或有所上升,而 50 岁以上成年人的心血管疾病发病率呈下降趋势。因此,目前的观察结果可能预示着在不久的将来,随着年轻人口的老龄化,心血管疾病可能会流行。在这篇综述中,我们讨论了 18-45 岁年轻人中缺血性心脏病、心力衰竭、心房颤动和心源性猝死的危险因素负担。此外,我们还讨论了这一年轻人群体中各种心血管疾病的流行率、发病率和时间趋势。