Bilen Ozlem, Wenger Nanette K
Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Emory Heart and Vascular Center, Atlanta, GA, USA.
F1000Res. 2020 Aug 19;9. doi: 10.12688/f1000research.20323.1. eCollection 2020.
Vascular aging leads to arterial hypertension, which is the leading cause of cardiovascular mortality and morbidity in older adults. Blood pressure reduction is effective in reducing the cardiovascular risk and is safe in ambulatory older adults. It is important to note that blood pressure control in this group of patients is challenging because of comorbidities, polypharmacy, and frailty. Choice of pharmacotherapy is not simple and should be individualized.
血管老化会导致动脉高血压,而动脉高血压是老年人心血管疾病死亡率和发病率的主要原因。降低血压对于降低心血管风险是有效的,并且对于非卧床的老年人来说是安全的。需要注意的是,由于存在合并症、多种药物治疗和身体虚弱,对这组患者进行血压控制具有挑战性。药物治疗的选择并不简单,应该个体化。