老年人的高血压管理
Hypertension management in older adults.
作者信息
Bilen Ozlem, Wenger Nanette K
机构信息
Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Emory Heart and Vascular Center, Atlanta, GA, USA.
出版信息
F1000Res. 2020 Aug 19;9. doi: 10.12688/f1000research.20323.1. eCollection 2020.
Abstract
Vascular aging leads to arterial hypertension, which is the leading cause of cardiovascular mortality and morbidity in older adults. Blood pressure reduction is effective in reducing the cardiovascular risk and is safe in ambulatory older adults. It is important to note that blood pressure control in this group of patients is challenging because of comorbidities, polypharmacy, and frailty. Choice of pharmacotherapy is not simple and should be individualized.
摘要
血管老化会导致动脉高血压，而动脉高血压是老年人心血管疾病死亡率和发病率的主要原因。降低血压对于降低心血管风险是有效的，并且对于非卧床的老年人来说是安全的。需要注意的是，由于存在合并症、多种药物治疗和身体虚弱，对这组患者进行血压控制具有挑战性。药物治疗的选择并不简单，应该个体化。
相似文献
1
Hypertension management in older adults.老年人的高血压管理
F1000Res. 2020 Aug 19;9. doi: 10.12688/f1000research.20323.1. eCollection 2020.
2
Pharmacological management of hypertension in the elderly and frail populations.老年人和体弱人群的高血压药物治疗管理。
Expert Rev Clin Pharmacol. 2018 Aug;11(8):805-817. doi: 10.1080/17512433.2018.1500896. Epub 2018 Jul 23.
3
Hypertension Management in Older and Frail Older Patients.老年及虚弱老年患者的高血压管理。
Circ Res. 2019 Mar 29;124(7):1045-1060. doi: 10.1161/CIRCRESAHA.118.313236.
4
[Hypertension in older adults].[老年人高血压]
Hipertens Riesgo Vasc. 2017;34 Suppl 2:26-29. doi: 10.1016/S1889-1837(18)30072-2.
5
Polypharmacy in the Aging Patient: Management of Hypertension in Octogenarians.高龄患者的多种药物治疗：八旬老人的高血压管理。
JAMA. 2015 Jul 14;314(2):170-80. doi: 10.1001/jama.2015.7517.
6
Hypertension Management at Older Age: An Update.老年高血压管理：最新进展
High Blood Press Cardiovasc Prev. 2019 Feb;26(1):27-36. doi: 10.1007/s40292-018-0290-z. Epub 2018 Nov 22.
7
Challenges in the Management of Hypertension in Older Populations.老年人群高血压管理中的挑战
Adv Exp Med Biol. 2017;956:167-180. doi: 10.1007/5584_2016_149.
8
Blood Pressure, Antihypertensive Polypharmacy, Frailty, and Risk for Serious Fall Injuries Among Older Treated Adults With Hypertension.老年高血压患者的血压、联合使用抗高血压药物、身体虚弱及严重跌倒受伤风险
Hypertension. 2017 Aug;70(2):259-266. doi: 10.1161/HYPERTENSIONAHA.116.09390. Epub 2017 Jun 26.
9
[Drug therapy for arterial hypertension and atrial fibrillation in frail patients : Are there any new insights and recommendations?].[老年患者动脉高血压和心房颤动的药物治疗：有哪些新见解和建议？]
Inn Med (Heidelb). 2024 May;65(5):517-523. doi: 10.1007/s00108-024-01681-8. Epub 2024 Mar 8.
10
Managing hypertension in older people: current concepts.老年人高血压管理：当前概念。
Drug Ther Bull. 2024 Sep 25;62(10):149-155. doi: 10.1136/dtb.2023.000031.
引用本文的文献
1
Influence of Ageing on the Pharmacodynamics and Pharmacokinetics of Chronically Administered Medicines in Geriatric Patients: A Review.衰老对老年患者长期用药药效学和药代动力学的影响：综述
Clin Pharmacokinet. 2025 Mar;64(3):335-367. doi: 10.1007/s40262-024-01466-0. Epub 2025 Jan 11.
2
The Problems and Needs of Self-Management Among Indonesian Older Adults With Hypertension: A Qualitative Study.印度尼西亚老年高血压患者自我管理的问题与需求：一项定性研究
SAGE Open Nurs. 2024 Oct 14;10:23779608241282915. doi: 10.1177/23779608241282915. eCollection 2024 Jan-Dec.
3
Interaction between hypertension and frailty and their impact on death risk in older adults: a follow-up study.高血压与衰弱的相互作用及其对老年人死亡风险的影响：一项随访研究。
BMC Geriatr. 2024 Feb 24;24(1):187. doi: 10.1186/s12877-024-04793-w.
4
Prevalence of non-communicable chronic diseases: arterial hypertension, diabetes mellitus, and associated risk factors in long-lived elderly people.非传染性慢性病的患病率：长寿老年人中的动脉高血压、糖尿病及其相关危险因素。
Rev Bras Enferm. 2023 Oct 9;76(4):e20220592. doi: 10.1590/0034-7167-2022-0592. eCollection 2023.
5
Chronological attenuation of NPRA/PKG/AMPK signaling promotes vascular aging and elevates blood pressure.随着时间的推移，NPRA/PKG/AMPK 信号的衰减会促进血管老化并升高血压。
Aging Cell. 2022 Sep;21(9):e13699. doi: 10.1111/acel.13699. Epub 2022 Aug 25.
6
Understanding perspectives on health-promoting behaviours among older adults with hypertension.了解高血压老年患者促进健康行为的观点。
Int J Qual Stud Health Well-being. 2022 Dec;17(1):2103943. doi: 10.1080/17482631.2022.2103943.
本文引用的文献
1
The relationship between adherence to a Dietary Approach to Stop Hypertension (DASH) dietary pattern and insomnia.遵循高血压饮食防治计划（DASH）饮食模式与失眠之间的关系。
BMC Psychiatry. 2019 Jul 30;19(1):234. doi: 10.1186/s12888-019-2220-6.
2
ACC/AHA Versus ESC/ESH on Hypertension Guidelines: JACC Guideline Comparison.ACC/AHA 与 ESC/ESH 高血压指南比较：JACC 指南比较。
J Am Coll Cardiol. 2019 Jun 18;73(23):3018-3026. doi: 10.1016/j.jacc.2019.03.507.
3
Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial.强化与标准血压控制对可能发生的痴呆的影响：一项随机临床试验。
JAMA. 2019 Feb 12;321(6):553-561. doi: 10.1001/jama.2018.21442.
4
Correction: Benefits and Harms of Intensive Blood Pressure Treatment in Adults Aged 60 Years or Older.更正：60岁及以上成年人强化血压治疗的益处与危害
Ann Intern Med. 2018 Apr 3;168(7):529-530. doi: 10.7326/L18-0077.
5
Achieved systolic blood pressure in older people: a systematic review and meta-analysis.老年人实现收缩压达标：系统评价和荟萃分析。
BMC Geriatr. 2017 Dec 5;17(1):279. doi: 10.1186/s12877-017-0672-4.
6
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.2017美国心脏病学会/美国心脏协会/美国医师协会/美国心脏病学学会/美国预防医学学院/美国老年病学会/美国药学协会/美国血液学会/美国预防医学学会/美国医学协会/美国初级保健医师学会成人高血压预防、检测、评估和管理指南：美国心脏病学会/美国心脏协会临床实践指南工作组报告
J Am Coll Cardiol. 2018 May 15;71(19):e127-e248. doi: 10.1016/j.jacc.2017.11.006. Epub 2017 Nov 13.
7
Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort.社区动脉粥样硬化风险（ARIC）队列研究中中年血管危险因素与25年痴呆症发病的关联
JAMA Neurol. 2017 Oct 1;74(10):1246-1254. doi: 10.1001/jamaneurol.2017.1658.
8
Magnitude of Hypotension Based on Office and Ambulatory Blood Pressure Monitoring: Results From a Cohort of 5066 Treated Hypertensive Patients Aged 80 Years and Older.基于诊室和动态血压监测的低血压程度：来自5066名80岁及以上接受治疗的高血压患者队列的结果
J Am Med Dir Assoc. 2017 May 1;18(5):452.e1-452.e6. doi: 10.1016/j.jamda.2017.01.015. Epub 2017 Feb 27.
9
Outcomes of Intensive Blood Pressure Lowering in Older Hypertensive Patients.老年高血压患者强化降压治疗的结局。
J Am Coll Cardiol. 2017 Feb 7;69(5):486-493. doi: 10.1016/j.jacc.2016.10.077.
10
Benefits and Harms of Intensive Blood Pressure Treatment in Adults Aged 60 Years or Older: A Systematic Review and Meta-analysis.老年人（年龄≥60 岁）强化降压治疗的获益与危害：系统评价与荟萃分析。
Ann Intern Med. 2017 Mar 21;166(6):419-429. doi: 10.7326/M16-1754. Epub 2017 Jan 17.
Zotero 插件