Faculty of Dentistry, Cairo University, Cairo, Egypt.
Faculty of Dentistry, Ahram Canadian University, Cairo, Egypt.
F1000Res. 2020 Feb 7;9:95. doi: 10.12688/f1000research.21999.2. eCollection 2020.
Extracranial meningioma is very rare with few cases reported, especially in the oral cavity. Its diagnosis is considered a challenge owing to the unusual site of occurrence. We report, to the best of our knowledge, the first case of extra-cranial meningioma as a primary tumor in the hard palate with no detected intracranial extension. A 59-year-old Egyptian female patient presented with a 22-year history of a large painless swelling at the right side of the hard palate, which could not be seen on radiographs. An incisional biopsy was taken and, after assessment with a panel of immunohistochemical markers, the lesion was diagnosed as extracranical grade I mengiothelial meningioma. The patient did not show up for surgical excision and follow-up was not performed because of the lose of contact with the patient. Intraoral meningioma is a rare tumor. Immuohistochemical markers are important for confirming this diagnosis.
颅外脑膜瘤非常罕见,报道的病例很少,尤其是在口腔内。由于发生部位不常见,其诊断被认为是一个挑战。据我们所知,我们报告了首例硬腭颅外脑膜瘤作为原发性肿瘤的病例,无颅内延伸。一名 59 岁埃及女性患者因右侧硬腭出现 22 年的大无痛肿胀而就诊,但 X 光片上未见异常。进行了切开活检,通过一组免疫组化标志物评估后,该病变被诊断为颅外 I 级脑膜上皮脑膜瘤。由于与患者失去联系,患者未进行手术切除,也未进行随访。口腔内脑膜瘤是一种罕见肿瘤。免疫组化标志物对于确认该诊断很重要。