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一名接受重大腹部手术后的患者出现严重登革热的非典型表现。

Atypical Presentation of Severe Dengue in a Patient following a Major Abdominal Surgery.

作者信息

Jayarajah Umesh, Basnayake Oshan, Nagodavithane Kavinda, Jayasinghe Jayan, Samarasekera Dharmabandhu N

机构信息

Professorial Surgical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.

Department of Surgery, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

出版信息

Case Rep Infect Dis. 2020 Aug 8;2020:2916107. doi: 10.1155/2020/2916107. eCollection 2020.

DOI:10.1155/2020/2916107
PMID:32850158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7436343/
Abstract

Severe dengue infections in a postoperative patient may lead to significant derangement in the body's homeostasis resulting in morbidity and sometimes even mortality. Reports on presentation and clinical manifestations of dengue in patients following major surgical procedures are scarce and restricted to few case reports. We describe a 26-year-old male with atypical presentation and late detection of dengue haemorrhagic fever following a major abdominal surgery. On postoperative day 6, he developed spontaneous bleeding from the drain site and moderate-to-massive bilateral pleural effusion with respiratory distress. His dengue IgM and IgG were positive. Therefore, a diagnosis of dengue haemorrhagic fever with bilateral lower zone pneumonia was made. A right-sided intercostal tube was inserted. Intensive care was given and was managed with intravenous antibiotics, targeted fluid therapy, and supportive care. He recovered from the infection and was discharged uneventfully. This case is unique because during the postoperative period, he went into critical phase with significant fluid leakage and developed bleeding manifestations without a clear febrile phase and deterioration in the haemodynamic parameters. High degree of suspicion and early detection are necessary to guide the fluid therapy and provide organ support in such patients.

摘要

术后患者发生严重登革热感染可能导致体内稳态严重紊乱,从而引发发病,有时甚至导致死亡。关于重大外科手术后患者登革热的表现和临床表现的报道很少,且仅限于少数病例报告。我们描述了一名26岁男性,在接受重大腹部手术后出现非典型表现且登革出血热检测延迟。术后第6天,他出现引流部位自发性出血以及中度至大量双侧胸腔积液并伴有呼吸窘迫。他的登革热IgM和IgG呈阳性。因此,诊断为登革出血热合并双侧下叶肺炎。插入了右侧肋间引流管。给予重症监护,并采用静脉抗生素、靶向液体治疗和支持性护理进行管理。他从感染中康复,顺利出院。该病例独特之处在于,在术后期间,他进入了伴有大量液体渗漏的关键阶段,且出现了出血表现,却没有明显的发热期,血流动力学参数也未恶化。对于此类患者,高度怀疑和早期检测对于指导液体治疗及提供器官支持至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165f/7436343/e2da376ecbb8/CRIID2020-2916107.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165f/7436343/4de46468a145/CRIID2020-2916107.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165f/7436343/ca1f3ef711b0/CRIID2020-2916107.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165f/7436343/e2da376ecbb8/CRIID2020-2916107.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165f/7436343/4de46468a145/CRIID2020-2916107.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165f/7436343/ca1f3ef711b0/CRIID2020-2916107.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165f/7436343/e2da376ecbb8/CRIID2020-2916107.003.jpg

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