Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, 201102, China.
Special Department of Vascular Anomalies, Tumor Hospital of Linyi City, Linyi, 276001, China.
World J Pediatr. 2021 Apr;17(2):123-130. doi: 10.1007/s12519-020-00379-9. Epub 2020 Aug 26.
Kasabach-Merritt phenomenon (KMP) is a rare disease that is characterized by severe thrombocytopenia and consumptive coagulation dysfunction caused by kaposiform hemangioendothelioma or tufted hemangioma. This condition primarily occurs in infants and young children, usually with acute onset and rapid progression. This review article introduced standardized recommendations for the pathogenesis, clinical manifestation, diagnostic methods and treatment process of KMP in China, which can be used as a reference for clinical practice.
卡波西-梅格特现象(KMP)是一种罕见疾病,其特征为伴有血小板减少症和消耗性凝血病的丛状血管瘤或上皮样血管内皮瘤。这种情况主要发生在婴儿和幼儿中,通常为急性发病且进展迅速。本文综述了中国 KMP 的发病机制、临床表现、诊断方法和治疗流程的规范化推荐意见,可为临床实践提供参考。