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注射吸毒者中的酒精使用障碍与丙型肝炎预防及护理:现状

Alcohol Use Disorder and Hepatitis C Prevention and Care in People Who Inject Drugs: The State of Play.

作者信息

Marcellin Fabienne, Jaquet Antoine, Lazarus Jeffrey V, Molina Patricia, Carrieri Patrizia

机构信息

Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, Marseille, France.

Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, UMR 1219, Bordeaux, France.

出版信息

Semin Liver Dis. 2021 May;41(2):109-116. doi: 10.1055/s-0040-1716343. Epub 2020 Aug 26.

Abstract

Safe and effective treatment with direct-acting antivirals (DAAs) has ushered in an era in which hepatitis C virus (HCV) elimination, as set out by the World Health Organization, is possible. However, alcohol use disorder (AUD) has the potential to reduce the benefits of prevention interventions and reduce access to and continuity of HCV care in at-risk populations, such as people who inject drugs (PWID). We review the literature on the consequences of AUD on the effectiveness of HCV prevention and the cascade of care in PWID and provide recommendations for future research in the field of alcohol use and HCV.

摘要

使用直接作用抗病毒药物(DAA)进行安全有效的治疗开创了一个时代,即按照世界卫生组织的规定消除丙型肝炎病毒(HCV)成为可能。然而,酒精使用障碍(AUD)有可能降低预防干预措施的益处,并减少高危人群(如注射吸毒者(PWID))获得丙型肝炎病毒治疗的机会以及治疗的连续性。我们回顾了关于酒精使用障碍对丙型肝炎病毒预防效果以及对注射吸毒者护理流程影响的文献,并为酒精使用与丙型肝炎病毒领域的未来研究提供建议。

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