Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, Kobe 657-8501, Japan.
Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
Food Funct. 2020 Sep 23;11(9):7321-7339. doi: 10.1039/d0fo01092h.
Black soybean (Glycine max L.), a cultivar containing abundant polyphenols in its seed coat such as anthocyanins and flavan-3-ols, has been reported to possess various health benefits toward lifestyle diseases. In this review article, the safety evaluation of polyphenol-rich black soybean seed coat extract (BE) and absorption of BE polyphenols are summarized. Additionally, we describe the antioxidant activity of BE polyphenols and their ability to induce antioxidant enzymes. The health benefits of BE and its polyphenols, such as anti-obesity and anti-hyperglycemic activities through the activation of AMP-activated protein kinase and translocation of glucose transporter 4, respectively, are also discussed. Furthermore, we found that black soybean polyphenols were involved in the improvement of vascular function. These emerging data require further investigation in scientific studies and human trials to evaluate the prevention of lifestyle diseases using black soybean polyphenols.
黑豆（Glycine max L.），一种种子种皮中富含多酚的品种，如花青素和黄烷醇 3-醇，据报道具有多种针对生活方式疾病的健康益处。在这篇综述文章中，总结了富含多酚的黑豆种皮提取物（BE）的安全性评价和 BE 多酚的吸收情况。此外，我们还描述了 BE 多酚的抗氧化活性及其诱导抗氧化酶的能力。还讨论了 BE 和其多酚的健康益处，例如通过激活 AMP 激活的蛋白激酶和葡萄糖转运蛋白 4 的易位分别发挥抗肥胖和抗高血糖作用。此外，我们发现黑豆多酚参与了血管功能的改善。这些新出现的数据需要在科学研究和人体试验中进一步研究，以评估使用黑豆多酚预防生活方式疾病的效果。
