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双侧声带麻痹的手术治疗方法。

Methods of surgical treatment of bilateral vocal fold paralysis.

机构信息

Chair and Department of Otolaryngology, Medical University of Warsaw, Warsaw, Poland, Poland.

出版信息

Endokrynol Pol. 2020;71(4):350-358. doi: 10.5603/EP.a2020.0042.

Abstract

Bilateral vocal fold paralysis presents as their complete or partial immobilisation. The median or paramedian position of vocal folds contributes to the narrowing of the airway at the level of the glottis and manifests as inspiratory dyspnoea. For many years iatrogenic injury of recurrent laryngeal nerves during thyroidectomy has been viewed as the most common underlying reason. It is very often a lifethreatening condition requiring not only corticosteroid administration and intubation, which only constitute a short-term symptomatic therapy, but also surgical intervention, including tracheostomy. The most common surgical methods implemented in bilateral vocal fold paralysis include posterior cordectomy, arytenoidectomy, and, more and more commonly, re-innervation. Other techniques used in restoring airway patency include laterofixation, botulinum toxin injection, and laryngeal stimulation, which is still under research. Stem cell and gene therapy are also being researched. Notably, the main purpose of surgical treatment is the provision of airway patency with the preservation of the phonatory and protective functions of the larynx.

摘要

双侧声带麻痹表现为声带完全或部分固定。声带的正中或旁正中位置导致声门水平气道变窄,并表现为吸气性呼吸困难。多年来,甲状腺切除术时喉返神经的医源性损伤一直被认为是最常见的潜在原因。这是一种非常危险的情况,不仅需要皮质类固醇治疗和插管,这仅构成短期对症治疗,还需要手术干预,包括气管切开术。在双侧声带麻痹中实施的最常见的手术方法包括后联合切除术、杓状软骨切除术,以及越来越常见的神经再支配术。用于恢复气道通畅的其他技术包括外侧固定术、肉毒毒素注射和喉刺激术,后者仍在研究中。干细胞和基因治疗也在研究中。值得注意的是,手术治疗的主要目的是提供气道通畅,同时保留喉的发声和保护功能。

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