Department of Cardiac Surgery.
Department of Congenital Cardiology, Mitera Hospital, Athens, Greece.
Curr Opin Cardiol. 2020 Nov;35(6):636-642. doi: 10.1097/HCO.0000000000000793.
Aberrant subclavian artery (ASCA) represents one of the most common congenital vascular anomalies of the aortic arch. The majority of ASCAs are associated with an aneurysm which occurs at their origin from the descending thoracic aorta, namely, the Kommerell's diverticulum. In this review, we discuss recent data with regards to indications of treatment and surgical management of these anatomical variants.
Various surgical methods have been described for the repair of ASCA and Kommerell's diverticulum. Traditionally, treatment included open surgery; however, recent studies describe a shift of conventional treatment to more hybrid or endovascular approaches. The heterogeneity in the anatomy and presentation of these clinical entities as well as patient-related factors have prevented conduction of randomized trials for the best available modality of treatment. This dearth of literature is well depicted in the current guidelines.
The optimal surgical procedure has to be tailored to every patient according to the presentation, individual anatomy, and patient's risk profile. Conventional surgery for ASCA and Kommerell's diverticulum has acceptable mortality and complication rates, whereas hybrid repairs report encouraging results. Further studies are required to provide sufficient evidence which will formulate a clear frame of treatment indications and optimal surgical methods, as well as evaluate long-term results following hybrid repair.
异常锁骨下动脉(ASCA)是主动脉弓最常见的先天性血管畸形之一。大多数 ASCA 与起源于降主动脉的动脉瘤相关,即 Kommerell 憩室。在这篇综述中,我们讨论了关于这些解剖变异的治疗指征和手术管理的最新数据。
已经描述了各种用于修复 ASCA 和 Kommerell 憩室的手术方法。传统上,治疗包括开放性手术;然而,最近的研究描述了将传统治疗方法转变为更混合或血管内方法的趋势。这些临床实体的解剖和表现的异质性以及与患者相关的因素阻碍了最佳治疗方法的随机试验的进行。这种文献的缺乏在当前的指南中得到了很好的体现。
根据临床表现、个体解剖结构和患者的风险状况,最优的手术方案需要针对每位患者进行定制。ASCA 和 Kommerell 憩室的传统手术具有可接受的死亡率和并发症发生率,而混合修复报告了令人鼓舞的结果。需要进一步的研究提供足够的证据,为治疗指征和最佳手术方法制定明确的框架,并评估混合修复后的长期结果。