高身体质量指数和夜班工作与医护人员的 COVID-19 有关。
High body mass index and night shift work are associated with COVID-19 in health care workers.
机构信息
Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.
Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
出版信息
J Endocrinol Invest. 2021 May;44(5):1097-1101. doi: 10.1007/s40618-020-01397-0. Epub 2020 Aug 27.
OBJECTIVE
To assess the magnitude of COVID-19 spread and the associated risk factors among health care workers (HCWs), we conducted an in-hospital survey in a central Italian COVID Hospital.
METHODS
Participants underwent nasopharyngeal swab and/or serum collection for SARS-CoV-2 IgG examination. We divided participants according to working status, into rotating-night shift workers (r-NSW) and day-workers.
RESULTS
We found 30 cases of COVID-19 infection in a total of 1180 HCWs (2.5%). Most COVID-19-positive hospital employees were r-NSWs with significantly higher BMI than that of individuals who tested negative. After adjustment for covariates, night work and BMI > 30 were associated with a markedly greater risk of COVID-19 diagnosis (OR 3.049 [95%CI 1.260-7.380] and OR 7.15 [95%CI 2.91-17.51], respectively).
CONCLUSIONS
Our results describe a low prevalence of COVID-19 infection among HCWs at a central Italian COVID Hospital. COVID-19 infection risk appears to be associated with obesity and night shift work, thus supporting the need for careful health surveillance among frontline HCWs exposed to COVID-19.
目的
为了评估 COVID-19 在医护人员（HCWs）中的传播程度和相关危险因素，我们在意大利中部的一家 COVID 医院进行了一项院内调查。
方法
参与者接受了鼻咽拭子和/或血清采集，以检查 SARS-CoV-2 IgG。我们根据工作状态将参与者分为轮值夜班工人（r-NSW）和日班工人。
结果
我们在总共 1180 名 HCWs 中发现了 30 例 COVID-19 感染病例（2.5%）。大多数 COVID-19 阳性的医院员工是 r-NSW，其 BMI 明显高于阴性检测结果的个体。在调整了协变量后，夜班工作和 BMI>30 与 COVID-19 诊断的显著更高风险相关（OR 3.049 [95%CI 1.260-7.380] 和 OR 7.15 [95%CI 2.91-17.51]）。
结论
我们的结果描述了意大利中部一家 COVID 医院的 HCWs 中 COVID-19 感染的低患病率。COVID-19 感染风险似乎与肥胖和夜班工作有关，因此支持对接触 COVID-19 的一线 HCWs 进行仔细的健康监测。
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