Department of Cardiothoracic Surgery, Great Ormond Street Hospital for Children, London, UK.
Section of Pediatric Cardiothoracic Surgery, St. Louis Children's Hospital, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Am J Transplant. 2021 Jan;21(1):15-20. doi: 10.1111/ajt.16282. Epub 2020 Sep 17.
Lung transplantation is a crucial component in the treatment of end-stage lung disease in infants. Traditionally, most lung transplants have been performed in older children and adults, resulting in a scarcity of data for infant patients. To address the challenges unique to this age group, novel strategies to provide the best preoperative, intraoperative, and postoperative care for these youngest patients are paramount. We review recent advances in bridge-to-transplantation therapy, including the use of a paracorporeal lung assist device, and differences in surgical technique, including bronchial artery revascularization, for incorporation into the overarching treatment strategy for infants undergoing lung transplantation.
肺移植是治疗婴儿终末期肺病的重要手段。传统上，大多数肺移植都是在年龄较大的儿童和成人中进行的，因此婴儿患者的数据非常有限。为了解决这个年龄段特有的挑战，为这些最小的患者提供最佳的术前、术中和术后护理的新策略至关重要。我们回顾了桥接移植治疗的最新进展，包括使用体外肺辅助装置，以及在手术技术方面的差异，包括支气管动脉血运重建，将其纳入接受肺移植的婴儿的总体治疗策略中。
