Department of Anesthesiology and Peri-operative Medicine, Mayo Clinic, Rochester, MN, USA.
METRIC-Multidisciplinary and Translational Research in Intensive Care Medicine, Mayo Clinic, Rochester, MN, USA.
J Trop Pediatr. 2021 Jul 2;67(3). doi: 10.1093/tropej/fmaa058.
Implementation of checklists has been shown to be effective in improving patient safety. This study aims to evaluate the effectiveness of implementation of a checklist for daily care processes into clinical practice of pediatric intensive care units (PICUs) with limited resources.
Prospective before-after study in eight PICUs from China, Congo, Croatia, Fiji, and India after implementation of a daily checklist into the ICU rounds.
Seven hundred and thirty-five patients from eight centers were enrolled between 2015 and 2017. Baseline stage had 292 patients and post-implementation 443. The ICU length of stay post-implementation decreased significantly [9.4 (4-15.5) vs. 7.3 (3.4-13.4) days, p = 0.01], with a nominal improvement in the hospital length of stay [15.4 (8.4-25) vs. 12.6 (7.5-24.4) days, p = 0.055]. The hospital mortality and ICU mortality between baseline group and post-implementation group did not show a significant difference, 14.4% vs. 11.3%; p = 0.22 for each. There was a variable impact of checklist implementation on adherence to various processes of care recommendations. A decreased exposure in days was noticed for; mechanical ventilation from 42.6% to 33.8%, p < 0.01; central line from 31.3% to 25.3%, p < 0.01; and urinary catheter from 30.6% to 24.4%, p < 0.01. Although there was an increased utilization of antimicrobials (89.9-93.2%, p < 0.01).
Checklists for the treatment of acute illness and injury in the PICU setting marginally impacted the outcome and processes of care. The intervention led to increasing adherence with guidelines in multiple ICU processes and led to decreased length of stay.
检查表的实施已被证明可有效提高患者安全性。本研究旨在评估在资源有限的儿科重症监护病房(PICU)中实施日常护理流程检查表的效果。
在中国、刚果民主共和国、克罗地亚、斐济和印度的 8 个 PICU 进行前瞻性前后对照研究,在 ICU 查房中实施每日检查表后。
2015 年至 2017 年间,8 个中心共纳入 735 名患者。基线阶段有 292 名患者,实施后有 443 名患者。实施后 ICU 住院时间明显缩短[9.4(4-15.5)vs. 7.3(3.4-13.4)天,p=0.01],住院时间也略有改善[15.4(8.4-25)vs. 12.6(7.5-24.4)天,p=0.055]。基线组和实施组的医院死亡率和 ICU 死亡率无显著差异,分别为 14.4%和 11.3%;p=0.22。检查表的实施对各种护理推荐流程的依从性有不同的影响。注意到机械通气、中心静脉置管和导尿管的暴露天数减少,分别为:从 42.6%降至 33.8%,p<0.01;从 31.3%降至 25.3%,p<0.01;从 30.6%降至 24.4%,p<0.01。尽管抗生素的使用率增加(89.9-93.2%,p<0.01)。
PICU 急性疾病和损伤治疗检查表对治疗结果和护理流程有一定影响。该干预措施导致 ICU 多个流程的指南依从性增加,住院时间缩短。