Geneva Transformative Governance Lab, Global Studies Institute, University of Geneva, Geneva, Switzerland; School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China.
Global Economic Dynamics and the Biosphere, The Royal Swedish Academy of Sciences, Stockholm, Sweden; Stockholm Resilience Centre, Stockholm University, Stockholm, Sweden.
Lancet Infect Dis. 2020 Dec;20(12):e307-e311. doi: 10.1016/S1473-3099(20)30392-3. Epub 2020 Aug 24.
Improving evidence for action is crucial to tackle antimicrobial resistance. The number of interventions for antimicrobial resistance is increasing but current research has major limitations in terms of efforts, methods, scope, quality, and reporting. Moving the agenda forwards requires an improved understanding of the diversity of interventions, their feasibility and cost-benefit, the implementation factors that shape and underpin their effectiveness, and the ways in which individual interventions might interact synergistically or antagonistically to influence actions against antimicrobial resistance in different contexts. Within the efforts to strengthen the global governance of antimicrobial resistance, we advocate for the creation of an international One Health platform for online learning. The platform will synthesise the evidence for actions on antimicrobial resistance into a fully accessible database; generate new scientific insights into the design, implementation, evaluation, and reporting of the broad range of interventions relevant to addressing antimicrobial resistance; and ultimately contribute to the goal of building societal resilience to this central challenge of the 21st century.
为了应对抗微生物药物耐药性，提高行动证据至关重要。针对抗微生物药物耐药性的干预措施数量正在增加，但目前的研究在努力程度、方法、范围、质量和报告方面存在重大局限性。要推动这项议程向前发展，就需要更好地了解干预措施的多样性、它们的可行性和成本效益、影响其有效性的实施因素，以及个体干预措施在不同情况下如何相互协同或拮抗地影响对抗抗微生物药物耐药性的行动。在加强抗微生物药物耐药性全球治理的努力中，我们倡导创建一个在线学习的全球卫生国际平台。该平台将把针对抗微生物药物耐药性的行动证据综合到一个完全可访问的数据库中；针对广泛干预措施的设计、实施、评估和报告，生成新的科学见解，以应对抗微生物药物耐药性；并最终有助于实现建立社会对 21 世纪这一核心挑战的韧性的目标。
