Wheldon D B, Slack M
J Clin Pathol. 1977 Jul;30(7):615-9. doi: 10.1136/jcp.30.7.615.
A prospective study of the bacterial populations of non-infected urine was mounted in an attempt to define the length of delay between voiding and analysis during which culture would not give false positive results due to the multiplication of contaminant bacteria present at the time of voiding. The findings suggest that culture of urine within four hours of voiding is likely to give a true indication of the presence or absence of infection. With further delay the interpretation of a heavy growth of bacteria in urine becomes progressively more unreliable, even if that growth is in pure culture.
为了确定排尿与分析之间的延迟时长，在此期间培养不会因排尿时存在的污染细菌繁殖而产生假阳性结果，对未感染尿液的细菌群落进行了一项前瞻性研究。研究结果表明，在排尿后四小时内对尿液进行培养，可能会真实显示是否存在感染。随着延迟时间的延长，即使尿液中大量细菌生长是纯培养物，对其生长情况的解读也会越来越不可靠。
